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. 2025 Feb 6;13(3):344.
doi: 10.3390/healthcare13030344.

How People in Eight European Countries Felt About the Safety, Effectiveness, and Necessity of COVID-19 Vaccination: A Cross-Sectional Survey

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How People in Eight European Countries Felt About the Safety, Effectiveness, and Necessity of COVID-19 Vaccination: A Cross-Sectional Survey

Kristien Coteur et al. Healthcare (Basel). .

Abstract

Background/objectives: Attitudes towards COVID-19 vaccination vary globally, influenced by political and cultural factors. This research aimed to assess the views of people without a healthcare qualification in Europe on COVID-19 vaccination safety, effectiveness, and necessity as well as how well informed they felt. The secondary outcomes focused on how respondents' views were affected by demographic and context factors and included a comparison by country of the level of feeling well informed. Methods: A mixed-method cross-sectional online survey in eight European countries, using convenience sampling. Results: A total of 1008 adults completed the survey, 60% of whom were female. While only 44.1% considered the vaccines safe, 43.5% effective, and 44.9% necessary, 80.0% had been vaccinated. Four in ten adults strongly agreed that they were well informed, while over a quarter did not answer the question. Younger respondents, well-informed individuals, and German respondents were more inclined to perceive COVID-19 vaccination as both effective and necessary. Conclusions: Motivations for vaccination included perceived health and social benefits, while concerns included a preference for "natural immunity", the rapid development of the vaccine, and potential unknown long-term effects. A correlation existed between respondents feeling well informed about the different COVID-19 vaccines in their country and the likelihood of having been vaccinated.

Keywords: COVID-19; Europe; SARS-CoV-2; population; public health; vaccination refusal; vaccine hesitancy; vaccine uptake.

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Conflict of interest statement

The authors declare no conflicts of interest.

References

    1. World Health Organization WHO COVID-19 Dash-Board 2024. [(accessed on 22 January 2025)]. Available online: https://data.who.int/dashboards/covid19.
    1. Gusev E., Sarapultsev A., Solomatina L., Chereshnev V. SARS-CoV-2-Specific Immune Response and the Pathogenesis of COVID-19. Int. J. Mol. Sci. 2022;23:1716. doi: 10.3390/ijms23031716. - DOI - PMC - PubMed
    1. Senevirathne T.H., Wekking D., Swain J.W.R., Solinas C., De Silva P. COVID-19: From emerging variants to vaccination. Cytokine Growth Factor Rev. 2024;76:127–141. doi: 10.1016/j.cytogfr.2023.11.005. - DOI - PubMed
    1. European Medicines Agency COVID-19 Vaccines: Studies for Approval. [(accessed on 14 May 2023)]. Available online: https://www.ema.europa.eu/en/human-regulatory/overview/public-health-thr....
    1. FDA FDA Adverse Event Reporting System (FAERS) Public Dashboard. [(accessed on 14 May 2023)]; Available online: https://www.fda.gov/drugs/questions-and-answers-fdas-adverse-event-repor....