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Review
. 2025 Mar;25(3):346-355.
doi: 10.1111/ggi.70003. Epub 2025 Feb 13.

Multidimensional insights about healthy aging from the cohort study for community-dwelling older adults: The SONIC study

Kei Kamide  1 , Kazunori Ikebe  2 , Yukie Masui  3 , Takeshi Nakagawa  4 , Mai Kabayama  1 , Hiroshi Akasaka  5 , Tomoaki Mameno  2 , Yuki Murotani  2 , Madoka Ogawa  4 , Saori Yasumoto  4 , Koichi Yamamoto  5 , Takumi Hirata  3 , Yasumichi Arai  6 , Yasuyuki Gondo  4 ; SONIC study group
Collaborators, Affiliations
Review

Multidimensional insights about healthy aging from the cohort study for community-dwelling older adults: The SONIC study

Kei Kamide et al. Geriatr Gerontol Int. 2025 Mar.

Abstract

The Septuagenarian, Octogenarian, Nonagenarian Investigation with Centenarian (SONIC) study was established considering population trends and targeting the oldest-old population. This study is unique in its narrow age range, consisting of individuals aged in their 70s, 80s and 90s, and is carried out as a longitudinal cohort study with follow ups every 3 years in urban and rural areas of eastern and western Japan. The aims of the SONIC study are primarily to clarify aging-related changes in multiple domains of human functioning, explore the dynamics of interactions among these domains and identify factors influencing healthy longevity, including psychological well-being. Investigations spanning medical, dental, nutritional, psychological and sociological fields were carried out by specialists, yielding important results. Findings from the SONIC study in Japan, a super-aged society, will provide valuable information for addressing the global aging trend. This review introduces the results from the SONIC study, and explains factors contributing to healthy longevity and happy aging. Geriatr Gerontol Int 2025; 25: 346-355.

Keywords: SONIC study; healthy longevity; longitudinal cohort; multidimensional aspects; oldest‐old population.

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Figures

Figure 1
Figure 1
The features of the Septuagenarian, Octogenarian, Nonagenarian Investigation with Centenarian (SONIC) study.
Figure 2
Figure 2
The overview of findings from the Septuagenarian, Octogenarian, Nonagenarian Investigation with Centenarian (SONIC) study. CVD, cardiovascular disease.
See this image and copyright information in PMC

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