Response to comments on inclusion of cryoprecipitate, pathogen-reduced on the WHO model lists of essential medicines for adults and children: a call for action

Affiliations

¹ McLean, Virginia, United States of America.
² Blood and other Products of Human Origin Team, WHO headquarters, Geneva, Switzerland.
³ Association Luxembourgeoise des Hémophiles, Luxembourg City, Luxembourg.
⁴ Sanquin Consulting Services, Amsterdam and Academic Institute IDTM, Groningen, The Netherlands.
⁵ Graduate Institute of Biomedical Materials and Tissue Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei, Taiwan.
⁶ International PhD Program in Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei, Taiwan.

Jay S Epstein et al. Blood Transfus. 2025 Mar.

. 2025 Mar;23(2):191-192.

doi: 10.2450/BloodTransfus.1005. Epub 2025 Jan 21.

¹ McLean, Virginia, United States of America.
² Blood and other Products of Human Origin Team, WHO headquarters, Geneva, Switzerland.
³ Association Luxembourgeoise des Hémophiles, Luxembourg City, Luxembourg.
⁴ Sanquin Consulting Services, Amsterdam and Academic Institute IDTM, Groningen, The Netherlands.
⁵ Graduate Institute of Biomedical Materials and Tissue Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei, Taiwan.
⁶ International PhD Program in Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei, Taiwan.

No abstract available

Conflict of interest statement

The Authors declare no conflicts of interest.

1. Makris M, Hermans C. Cryoprecipitate should not be the essential medicine recommended by the WHO to treat hemophilia. Blood Transfus. 2025;23(2):187–188. doi: 10.2450/BloodTransfus.974. - DOI - PMC - PubMed
1. Pierce GF, O’Mahony B, Kaczmarek R, Mekhuzla S, Skinner MW. Recommending defunct therapies is a safety risk for hemophilia. Blood Transfus. 2025;23(2):189–190. doi: 10.2450/BloodTransfus.982. - DOI - PMC - PubMed
1. Epstein JS, Maryuningsih Y, Faber JC, Smid WM, Burnouf T. Inclusion of cryoprecipitate, pathogen-reduced, in the WHO model lists of essential medicines for adults and children: a call for action. Blood Transfus. 2024;22:481–483. doi: 10.2450/BloodTransfus.687. - DOI - PMC - PubMed
1. Srivastava A. The case for equitable haemophilia care. Lancet Haematol. 2021;8(9):e626. doi: 10.1016/S2352-3026(21)00132-0. - DOI - PubMed
1. Mishra DK, Rath A, Parihar M, Vinarkar SS, Kundu A. Current diagnosis of bleeding disorders in lower income countries. Int J Lab Hematol. 2025;47(1):36–40. doi: 10.1111/ijlh.14377. - DOI - PubMed