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. 2025 Feb 11;5(1):e35.
doi: 10.1017/ash.2025.17. eCollection 2025.

Impact of a cerebrospinal fluid diagnostic stewardship intervention on quantity of tests, length of stay, antibiotic prescriptions, and cost

Aaron Pathak  1 , Sabra Shay  2 , Todd Lasco  3 , Mayar Al Mohajer  4
Affiliations

Impact of a cerebrospinal fluid diagnostic stewardship intervention on quantity of tests, length of stay, antibiotic prescriptions, and cost

Aaron Pathak et al. Antimicrob Steward Healthc Epidemiol. .

Abstract

Redundant and low-value cerebrospinal fluid analysis for suspected meningitis can increase costs and antimicrobial use. Our diagnostic stewardship intervention limited available infectious disease cerebrospinal fluid assays to seven common tests, including a multiplex polymerase chain reaction panel. There was no significant difference in the cost of testing or clinical outcomes.

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Conflict of interest statement

All authors report no conflicts of interest relevant to this article.

References

    1. Hasbun R. Progress and challenges in bacterial meningitis: a review. JAMA 2022;328:2147–2154. - PubMed
    1. Morgan DJ, Malani P, Diekema DJ. Diagnostic stewardship—leveraging the laboratory to improve antimicrobial use. JAMA 2017;318:607–608. - PubMed
    1. Banerjee R. Multiplex polymerase chain reaction testing to diagnose central nervous system infections—a doubled-edged sword. J Pediatr Infect Dis Soc 2022;11:124–125. - PubMed
    1. Morrison AR, Jones MC, Makowski CT, et al. Evaluation of the selection of cerebrospinal fluid testing in suspected meningitis and encephalitis. Diagn Microbiol Infect Dis 2022;102:115571. - PubMed
    1. Pathak A, Pham C, Shay S, Lasco T, Mohajer MA. The impact of the FilmArray meningitis/encephalitis panel on empiric antibiotic prescriptions in patients with suspected community-acquired meningitis. Antimicrob Steward Healthc Epidemiol 2024;4:e104. - PMC - PubMed

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