Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1985;240(2):271-6.
doi: 10.1007/BF00222334.

Mitotic activity of gonadotropes in the anterior pituitary of the castrated male rat

K Inoue, S Tanaka, K Kurosumi

Mitotic activity of gonadotropes in the anterior pituitary of the castrated male rat

K Inoue et al. Cell Tissue Res. 1985.

Abstract

The proliferation of gonadotropes in the anterior pituitary of the castrated male rat was examined immunohistochemically after colchicine treatment. The results show a more than 10-fold increase in mitotic frequency in gonadotropes 1 or 2 weeks after castration, as compared with controls. This result explains the increase in the population of immunoreactive LH cells in castrated male rats. The gonadotropes decreased significantly 1 month after castration. The mitotic activity of gonadotropes was almost completely suppressed in castrates implanted with a silastic tube filled with testosterone.

PubMed Disclaimer

References

    1. J Endocrinol. 1984 Apr;101(1):87-94 - PubMed
    1. Endocrinology. 1954 May;54(5):516-41 - PubMed
    1. Acta Endocrinol (Copenh). 1970 Jun;64(2):324-38 - PubMed
    1. Biochem J. 1956 Feb;62(2):315-23 - PubMed
    1. Am J Physiol. 1968 Jan;214(1):158-60 - PubMed