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Case Reports
. 1985 Mar;15(2):95-9.
doi: 10.1111/j.1365-2222.1985.tb02261.x.

Isolated late asthmatic reaction due to nickel sulphate without antibodies to nickel

J L Malo, A Cartier, G Gagnon, S Evans, J Dolovich
Case Reports

Isolated late asthmatic reaction due to nickel sulphate without antibodies to nickel

J L Malo et al. Clin Allergy. 1985 Mar.

Abstract

A worker with occupational exposure to nickel developed asthma a few months after starting work. Skin prick tests to nickel sulphate were negative. Inhalation challenge with nickel sulphate, at a concentration of 10 mg/ml for 30 min induced a late asthmatic reaction, starting 3 hr after the end of exposure leading to severe nocturnal attack. Tests for antibodies with nickel reactivity were negative.

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