Funding Support and Author Disclosures Dr Sedrak is supported in part by grants K76AG074918, R21CA277660, and R01CA280088. Dr Asnani is supported in part by grant R01HL163172. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health or any other funders. Dr Sedrak has received research funding to the institution from Eli Lilly, Novartis, Seattle Genetics, and Pfizer Foundation (outside the submitted work). Dr Asnani is a member of the board of directors of Corventum; receives patent royalties from Mass General Brigham; and serves as the principal investigator of a sponsored research agreement with Genentech (all unrelated to the present work).