Changes in spatial selectivity of pattern-ERG components with stimulus contrast

Abstract

Electrical mass responses of the visual system to stripe patterns of varying fineness (spatial frequency) can show either an amplitude maximum at a medium spatial frequency, a behavior termed "spatial selectivity," or a monotonic decrease in amplitude with increasing spatial frequency. The former behavior is probably mediated by neurons having a center-surround receptive field structure and the latter by neurons lacking this antagonism. The pattern-evoked human electroretinogram was studied in this report using different spatial frequencies and pattern contrasts. The positive component of the response showed a spatial selectivity only at low contrast but was not spatially selective at the highest contrast. The negative component showed a spatial selectivity at all contrast levels. The data indicate that if pattern-related responses activated by antagonistic receptive fields are to be studied, low contrast values should be employed and attention should be paid to the negative component of the response.