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Review
. 2025 May;39(2):102041.
doi: 10.1016/j.berh.2025.102041. Epub 2025 Feb 18.

Tropical pyomyositis

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Review

Tropical pyomyositis

Praveen Kumar Tirlangi et al. Best Pract Res Clin Rheumatol. 2025 May.

Abstract

Tropical pyomyositis is a serious infectious disease characterised by the formation of abscesses in the skeletal muscles and is primarily caused by Staphylococcus aureus, with an increasing incidence in non-tropical regions. The disease primarily affects men and young adults, often following minor trauma, with an increasing incidence in immunocompromised individuals. Immunocompromised hosts are more likely to be affected by Gram-negative organisms, Mycobacterium tuberculosis, opportunistic infections such as fungal pathogens, non-tuberculous mycobacteria, and Nocardia species. Diagnosis is complicated by non-specific symptoms and the low yield of blood cultures, so imaging studies such as Magnetic Resonance Imaging (MRI) are required for accurate identification. Treatment focuses on controlling the source through drainage, tailored antibiotic therapy, and supportive care, especially in patients with complications such as multi-organ dysfunction. Given the complex clinical manifestations, heightened awareness and a collaborative approach to education and resource provision are critical to improving outcomes in patients with tropical pyomyositis.

Keywords: Abscess; Staphylococcus aureus; Tropical pyomyositis.

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Conflict of interest statement

Declaration of interest statement The authors declare that there is no conflict of interest regarding the publication of the chapter titled "Tropical Pyomyositis," submitted for inclusion in Best Practice & Research Clinical Rheumatology, Issue 39.2. No financial, personal, or professional affiliations exist that could influence or bias the content of this work.

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