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Review
. 2025 Apr;65(4):e70004.
doi: 10.1002/jobm.70004. Epub 2025 Feb 19.

The Interactive Dynamics of Pseudomonas aeruginosa in Global Ecology

Telma de Sousa  1   2   3   4 , Catarina Silva  4 , Gilberto Igrejas  1   2   3 , Michel Hébraud  5 , Patrícia Poeta  3   4   6   7
Affiliations
Review

The Interactive Dynamics of Pseudomonas aeruginosa in Global Ecology

Telma de Sousa et al. J Basic Microbiol. 2025 Apr.

Abstract

Pseudomonas aeruginosa is an opportunistic bacterium widely distributed in both natural and urban environments, playing a crucial role in global microbial ecology. This article reviews the interactive dynamics of P. aeruginosa across different ecosystems, highlighting its capacity for adaptation and resistance in response to environmental and therapeutic pressures. We analyze the mechanisms of antibiotic resistance, including the presence of resistance genes and efflux systems, which contribute to its persistence in both clinical and nonclinical settings. The interconnection between human, animal, and environmental health, within the context of the One Health concept, is discussed, emphasizing the importance of monitoring and sustainable management practices to mitigate the spread of resistance. Through a holistic approach, this work offers insights into the influence of P. aeruginosa on public health and biodiversity.

Keywords: MDR; Pseudomonas aeruginosa; environmental impact; microbial ecology.

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