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Conflicts of Interest: The author has completed the ICMJE uniform disclosure form (available at https://tcr.amegroups.com/article/view/10.21037/tcr-24-1952/coif). The author has no conflicts of interest to declare.
Ng J, Cai L, Girard L, Prall OWJ, Rajan N, Khoo C, Batrouney A, Byrne DJ, Boyd DK, Kersbergen AJ, Christie M, Minna JD, Burr ML, Sutherland KD.Ng J, et al.Clin Cancer Res. 2024 May 1;30(9):1846-1858. doi: 10.1158/1078-0432.CCR-23-2360.Clin Cancer Res. 2024.PMID: 38180245Free PMC article.
References
Gay CM, Stewart CA, Park EM, et al. Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities. Cancer Cell 2021;39:346-360.e7. 10.1016/j.ccell.2020.12.014
-
DOI
-
PMC
-
PubMed
Rudin CM, Durinck S, Stawiski EW, et al. Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer. Nat Genet 2012;44:1111-6. 10.1038/ng.2405
-
DOI
-
PMC
-
PubMed
Baine MK, Hsieh MS, Lai WV, et al. SCLC Subtypes Defined by ASCL1, NEUROD1, POU2F3, and YAP1: A Comprehensive Immunohistochemical and Histopathologic Characterization. J Thorac Oncol 2020;15:1823-35. 10.1016/j.jtho.2020.09.009
-
DOI
-
PMC
-
PubMed
Ng J, Cai L, Girard L, et al. Molecular and Pathologic Characterization of YAP1-Expressing Small Cell Lung Cancer Cell Lines Leads to Reclassification as SMARCA4-Deficient Malignancies. Clin Cancer Res 2024;30:1846-58. 10.1158/1078-0432.CCR-23-2360
-
DOI
-
PMC
-
PubMed
Nicholson AG, Tsao MS, Beasley MB, et al. The 2021 WHO Classification of Lung Tumors: Impact of Advances Since 2015. J Thorac Oncol 2022;17:362-87. 10.1016/j.jtho.2021.11.003
-
DOI
-
PubMed