Balancing risks and benefits in the treatment of patients with Bacillus Calmette-Guerin-unresponsive high-risk non-muscle-invasive bladder cancer
- PMID: 39974809
- PMCID: PMC11833534
- DOI: 10.21037/tau-24-529
Balancing risks and benefits in the treatment of patients with Bacillus Calmette-Guerin-unresponsive high-risk non-muscle-invasive bladder cancer
Keywords: Atezolizumab; Bacillus Calmette-Guerin-unresponsive (BCG-unresponsive); circulating-tumour DNA (ctDNA); immuno-oncology; non-muscle-invasive bladder cancer (NMIBC).
Conflict of interest statement
Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://tau.amegroups.com/article/view/10.21037/tau-24-529/coif). R.T.B. has received research funding from the UK NIHR HTA programme, Cancer Research UK, Janssen, University Hospitals Birmingham Charity (UK), QED Therapeutics (USA), and UroGen Pharma (USA). He is an unpaid charity trustee for Action Bladder Cancer UK (UK), an advisory board member for Nonacus Limited (UK), and receives consultancy fees from Cystotech ApS (Denmark) and Informed Genomics Limited (UK). The other authors have no conflicts of interest to declare.
Comment on
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Phase 2 Trial of Atezolizumab in Bacillus Calmette-Guérin-unresponsive High-risk Non-muscle-invasive Bladder Cancer: SWOG S1605.Eur Urol. 2023 Dec;84(6):536-544. doi: 10.1016/j.eururo.2023.08.004. Epub 2023 Aug 16. Eur Urol. 2023. PMID: 37596191 Free PMC article. Clinical Trial.
References
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- Catto JWF, Khetrapal P, Ricciardi F, et al. Effect of Robot-Assisted Radical Cystectomy With Intracorporeal Urinary Diversion vs Open Radical Cystectomy on 90-Day Morbidity and Mortality Among Patients With Bladder Cancer: A Randomized Clinical Trial. JAMA 2022;327:2092-103. 10.1001/jama.2022.7393 - DOI - PMC - PubMed
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