The mechanism of perilla oil in regulating lipid metabolism
- PMID: 39977980
- DOI: 10.1016/j.foodchem.2025.143318
The mechanism of perilla oil in regulating lipid metabolism
Abstract
Emerging science supports the role of lipid metabolism disorders in the occurrence and development of chronic diseases. Dietary intervention has been shown to be an effective strategy for regulating lipid metabolism. Recent studies showed that perilla is rich in various effective ingredients, including fatty acids, flavonoids, and phenolic acids. These ingredients exhibit a myriad of benefits, notably enhancing intestinal health and helping to manage metabolic diseases. Perilla oil stands out as a promising agent for regulating lipid metabolism, underscoring its potential for various health applications. This review introduces the active ingredients in perilla and provides a systematic overview of the mechanism by which perilla oil regulates lipid metabolism to expand its application value. Further research should focus on exploring the dose effect and absorption efficiency of perilla oil in clinical applications.
Keywords: Intestinal microflora; Lipid metabolism; Perilla oil; Signaling pathways.
Copyright © 2025 Elsevier Ltd. All rights reserved.
Conflict of interest statement
Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. No new data were generated in this paper.
Similar articles
-
Effects of dietary perilla seed oil supplementation on lipid metabolism, meat quality, and fatty acid profiles in Yellow-feathered chickens.Poult Sci. 2019 Nov 1;98(11):5714-5723. doi: 10.3382/ps/pez358. Poult Sci. 2019. PMID: 31376347
-
Perilla Oil Decreases Aortic and Hepatic Lipid Accumulation by Modulating Lipogenesis and Lipolysis in High-Fat Diet-Fed Mice.J Med Food. 2019 Jan;22(1):14-21. doi: 10.1089/jmf.2018.4226. Epub 2018 Sep 12. J Med Food. 2019. PMID: 30207814
-
α-Lipoic acid ameliorated oxidative stress induced by perilla oil, but the combination of these dietary factors was ineffective to cause marked deceases in serum lipid levels in rats.Nutr Res. 2017 Dec;48:49-64. doi: 10.1016/j.nutres.2017.10.009. Epub 2017 Oct 12. Nutr Res. 2017. PMID: 29246281
-
Perilla Seed Oil and Protein: Composition, Health Benefits, and Potential Applications in Functional Foods.Molecules. 2024 Nov 7;29(22):5258. doi: 10.3390/molecules29225258. Molecules. 2024. PMID: 39598647 Free PMC article. Review.
-
Perilla Seed Oil: A Review of Health Effects, Encapsulation Strategies and Applications in Food.Foods. 2024 Nov 13;13(22):3615. doi: 10.3390/foods13223615. Foods. 2024. PMID: 39594031 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources