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. 2025 Sep-Oct;29(5):533-534.
doi: 10.1177/12034754251320632. Epub 2025 Feb 20.

Severe Cutaneous Adverse Reactions Associated with Immune Checkpoint Inhibitors: A Systematic Review of Clinical Characteristics and Management

Siddhartha Sood  1 , Ahmed Bagit  1 , Jihad Abou Ali Waked  2 , Jonah Perlmutter  1 , Nawar Tarafdar  2 , Khalad Maliyar  3 , Muskaan Sachdeva  3 , Abrahim Abduelmula  3 , Asfandyar Mufti  3   4 , Jensen Yeung  3   4   5   6
Affiliations

Severe Cutaneous Adverse Reactions Associated with Immune Checkpoint Inhibitors: A Systematic Review of Clinical Characteristics and Management

Siddhartha Sood et al. J Cutan Med Surg. 2025 Sep-Oct.
No abstract available

Keywords: Stevens-Johnson syndrome; acute generalized exanthematous pustulosis; drug reaction with eosinophilia and systemic symptoms; immune checkpoint inhibitor; severe cutaneous adverse reaction; systematic review; toxic epidermal necrolysis.

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Conflict of interest statement

Declaration of Conflicting InterestsThe author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: Dr. Asfandyar Mufti has been a speaker for AbbVie and Janssen.Dr. Jensen Yeung has been an adviser, consultant, speaker, and/or investigator for AbbVie, Amgen, Anacor, Arcutis, Astellas, Bausche, Baxalta, Boehringer Ingelheim, Bristol Myers Squibb, Celgene, Centocor, Coherus, Dermira, Forward, Fresenius Kabi, Galderma, Incyte, Janssen, LEO Pharma, MedImmune, Merck, Novartis, Pfizer, Regeneron, Roche, Sanofi Genzyme, Sun Pharma, Takeda, UCB, and Xenon.The remaining authors Mr. Sood, Mr. Bagit, Mr. Waked, Mr. Perlmutter, Ms. Tarafdar, Dr. Maliyar, Dr. Sachdeva, and Dr. Abduelmula have no relevant disclosures.

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