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Case Reports
. 1985 May;12(5 Pt 2):914-7.
doi: 10.1016/s0190-9622(85)70112-0.

Hyperpigmentation in megaloblastic anemia

V J Marks, R A Briggaman, C E Wheeler Jr
Case Reports

Hyperpigmentation in megaloblastic anemia

V J Marks et al. J Am Acad Dermatol. 1985 May.

Abstract

Generalized hyperpigmentation developed over 2 years in a 65-year-old woman. A diagnosis of pernicious anemia was made, and treatment with vitamin B12 led to complete reversion of her hyperpigmentation to normal. Literature pertinent to hyperpigmentation and its association with megaloblastic anemias is reviewed and several possible mechanisms are mentioned.

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