Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1985 Jan;16(1):1-5.
doi: 10.1016/0306-9877(85)90034-9.

Why was the 1918 influenza pandemic so lethal? The possible role of a neurovirulent neuraminidase

C P Maurizi

Why was the 1918 influenza pandemic so lethal? The possible role of a neurovirulent neuraminidase

C P Maurizi. Med Hypotheses. 1985 Jan.

Abstract

Epidemiological, viral, behavioral and neuropathological evidence suggests that some influenza epidemics were neurovirulent. Re-examination of the data from the lethal 1918 pandemic armed with recent observations about the influenza virus implicates a neurovirulent influenza virus in manic-depressive disease, schizophrenia and Parkinson's disease. The neurovirulence seems to have been related to the species of neuraminidase.

PubMed Disclaimer

LinkOut - more resources