Teclistamab in relapsed systemic sclerosis after autologous haematopoietic stem cell transplantation

Elise Siegert¹, Robert Biesen¹, Maria Dzamukova², Christian Furth³, Meike Probst⁴, Felix Doellinger⁵, Thula Walter-Rittel⁵, Anja Fleischmann², Artur Wilhelm², Anne Elisabeth Beenken², Edgar Wiebe¹, Ann-Christin Pecher⁶, Jörg Henes⁶, Stefan Florian⁷, David Simon¹, Arnd Kleyer¹, Gerd-Rüdiger Burmester², Ulrich Keller⁸, Jan Krönke⁸, Gerhard Krönke², Tobias Alexander⁹

Affiliations

¹ Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
² Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany; German Rheumatology Research Centre (DRFZ) Berlin, a Leibniz Institute, Berlin, Germany.
³ Department of Nuclear Medicine, Charité - Universitätsmedizin Berlin corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
⁴ Department of Infectious Diseases, Respiratory and Critical Care Medicine, Charité - Universitätsmedizin Berlin corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
⁵ Department of Radiology, Charité - Universitätsmedizin Berlin corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
⁶ Center for Interdisciplinary Rheumatology, Immunology and Autoimmune Diseases (INDIRA) and Department for Internal Medicine II (Hematology, Oncology, Rheumatology and Immunology), Universitätsklinikum Tübingen, Tübingen, Germany.
⁷ Institute of Pathology, Charité - Universitätsmedizin Berlin corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
⁸ Department of Hematology, Oncology and Cancer Immunology, Charité - Universitätsmedizin Berlin corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany; German Center for Translational Cancer Research (DKTK), Partner Site Berlin, Berlin, Germany.
⁹ Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany; German Rheumatology Research Centre (DRFZ) Berlin, a Leibniz Institute, Berlin, Germany. Electronic address: tobias.alexander@charite.de.

PMID: 40000264
DOI: 10.1016/j.ard.2025.01.043

Teclistamab in relapsed systemic sclerosis after autologous haematopoietic stem cell transplantation

Elise Siegert et al. Ann Rheum Dis. 2025 Apr.

. 2025 Apr;84(4):653-656.

doi: 10.1016/j.ard.2025.01.043. Epub 2025 Feb 24.

Authors

Affiliations

¹ Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
² Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany; German Rheumatology Research Centre (DRFZ) Berlin, a Leibniz Institute, Berlin, Germany.
³ Department of Nuclear Medicine, Charité - Universitätsmedizin Berlin corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
⁴ Department of Infectious Diseases, Respiratory and Critical Care Medicine, Charité - Universitätsmedizin Berlin corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
⁵ Department of Radiology, Charité - Universitätsmedizin Berlin corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
⁶ Center for Interdisciplinary Rheumatology, Immunology and Autoimmune Diseases (INDIRA) and Department for Internal Medicine II (Hematology, Oncology, Rheumatology and Immunology), Universitätsklinikum Tübingen, Tübingen, Germany.
⁷ Institute of Pathology, Charité - Universitätsmedizin Berlin corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
⁸ Department of Hematology, Oncology and Cancer Immunology, Charité - Universitätsmedizin Berlin corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany; German Center for Translational Cancer Research (DKTK), Partner Site Berlin, Berlin, Germany.
⁹ Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany; German Rheumatology Research Centre (DRFZ) Berlin, a Leibniz Institute, Berlin, Germany. Electronic address: tobias.alexander@charite.de.

PMID: 40000264
DOI: 10.1016/j.ard.2025.01.043

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Conflict of interest statement

Competing interests JH received speakers fee or honoraria from Janssen-Cilag. JK received honoraria and support for attending meetings from Johnson & Johnson. DS received grants or contracts from Johnson & Johnson and consulting fees from Janssen-Cilag. AK received consulting fees from Janssen Pharmaceutica. UK received travel support, honoraria for advisory boards and invited lectures from Johnson & Johnson/Janssen Germany. GK received honoraria for advisory boards and invited lectures from Johnson & Johnson. TA received a study grant from Johnson & Johnson. ES, RB, MD, CF, SF, MP, FD, TWR, AF, AW, AB, EW, ACP, AK, and GRB declared no conflict of interest in relation to this manuscript.

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Teclistamab in relapsed systemic sclerosis after autologous haematopoietic stem cell transplantation

Affiliations

Teclistamab in relapsed systemic sclerosis after autologous haematopoietic stem cell transplantation

Authors

Affiliations

Conflict of interest statement

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