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. 2025 Mar;19(5):139-147.
doi: 10.1080/17520363.2025.2468144. Epub 2025 Feb 26.

Prognostic value of HALP score in predicting in-hospital mortality in patients with NSTEMI

Dogan Ilis  1 , Ayca Arslan  1 , Inanc Artac  1 , Muammer Karakayali  1 , Timor Omar  1 , Serif Hamideyin  2 , Hatice Taşkan  3 , Ozcan Yagicibulut  4 , Yavuz Karabag  1 , Ibrahim Rencuzogullari  1
Affiliations

Prognostic value of HALP score in predicting in-hospital mortality in patients with NSTEMI

Dogan Ilis et al. Biomark Med. 2025 Mar.

Abstract

Aims: We aimed to investigate the association between the HALP score and in-hospital mortality in patients with non-ST segment myocardial infarction (NSTEMI).

Materials and methods: In this retrospective study participants were divided into two groups, based on the median HALP score. Findings were compared between the groups.

Results: A total of 1648 patients included. The median HALP score cutoff value was 3.87. While the low HALP score group (<3.87) included 824 patients, the high HALP score group (>3.87) included 824 patients. Patients with the low HALP score were older and had a higher prevalence of comorbidities. A HALP score ≤ 2.62 predicted in-hospital mortality with sensitivity of 72.5% and a specificity of 77.3% (area under curve 0.809), according to ROC curve analysis. In multivariate analysis, age, diastolic blood pressure, Killip Class > 1 and Syntax Score, creatinine level, LVEF and HALP Score (OR: 0.504, 95% CI: 0.415-0.613; p < 0.001) were independently associated with in-hospital mortality.

Conclusions: According to the current study, the HALP score was independently associated with in-hospital mortality in patients with NSTEMI. Moreover, HALP score might be used as a predictor of in-hospital mortality in this population.

Keywords: HALP score; NSTEMI; Non-ST segment myocardial infarction; mortality; myocardial ischemia.

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Conflict of interest statement

The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.

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