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Editorial
. 2025 Apr 14;20(8):e202401017.
doi: 10.1002/cmdc.202401017. Epub 2025 Feb 26.

A Career Doing STUFF

Michael M Hann  1
Affiliations
Editorial

A Career Doing STUFF

Michael M Hann. ChemMedChem. .

Abstract

In this Guest Editorial for the MedChem Musings series, Mike, Former Senior Research Director at GSK, reflects on a career doing "STUFF": Science, Technology, Useful Functions and Fun. Mike summarises some of the many things he has been involved in throughout his 45 year-career in drug discovery, from which future generations of researchers can hopefully find practical advice and inspiration.

Keywords: AI/ML; Career; Computational Chemistry; Fragments; Intracellular Free Drug measurements; Molecular Complexity; Molecular Obesity; Target Tractability.

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References

    1. M. M. Hann, P. G. Sammes, P. D. Kennewell, J. B. Taylor, J. Chem. Soc. Perkin 1 1982, 307–314.
    1. M. M. Hann, A C. White, Thiomorpholine Derivatives, US4427676A, 1981.
    1. D. Donald, M. . M. Hann, J. Saunders, H. Wadsworth, Thiol based Collagenase Inhibitors, US4595700A, 1985.
    1. K. McCullagh, H. Wadsworth, M. . M. Hann, Carboxyalkyl Peptide Derivatives, US4568666A, 1984.
    1. W. Warr, An interview with Tony Hopfinger, https://www.warr.com/Hopfingerinterviewfinal.pdf.

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