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. 2025 Mar:183:225-236.
doi: 10.1016/j.jpsychires.2025.02.016. Epub 2025 Feb 18.

Prevalence, age-of-onset, and course of mental disorders among 72,288 first-year university students from 18 countries in the World Mental Health International College Student (WMH-ICS) initiative

Andre Mason  1 Charlene Rapsey  2 Nancy Sampson  3 Sue Lee  4 Yesica Albor  5 Ahmad N Al-Hadi  6 Jordi Alonso  7 Nouf Al-Saud  8 Yasmin Altwaijri  9 Claes Andersson  10 Lukoye Atwoli  11 Randy P Auerbach  12 Caroline Ayuya  13 Patricia M Báez-Mansur  14 Laura Ballester  15 Jason Bantjes  16 Harald Baumeister  17 Marcus Bendtsen  18 Corina Benjet  19 Anne H Berman  20 Erik Bootsma  21 Silver C N Chan  22 Irina Cohut  23 María Anabell Covarrubias Díaz Couder  24 Pim Cuijpers  25 Oana David  26 Dong Dong  27 David D Ebert  28 Mireia Felez Nobrega  29 Jorge Gaete  30 Carlos García Forero  31 Margalida Gili  32 Raúl Gutiérrez-García  33 Josep Maria Haro  34 Penelope Hasking  35 Kristen Hudec  36 Xanthe Hunt  37 Petra Hurks  38 Mathilde Husky  39 Florence Jaguga  40 Leontien Jansen  41 Fanny Kählke  42 Elisabeth Klinkenberg  43 Ann-Marie Küchler  44 Álvaro I Langer  45 Irene Léniz  46 Yan Liu  47 Scarlett Mac-Ginty  48 Vania Martínez  49 Muthoni Mathai  50 Margaret McLafferty  51 Andrea Miranda-Mendizabal  52 Elaine Murray  53 Catherine M Musyoka  54 Catalin Nedelcea  55 Chun Ho Ngai  56 Daniel Núñez  57 Siobhan O'Neill  58 Jose A Piqueras  59 Codruta A Popescu  60 Kealagh Robinson  61 Tiscar Rodriguez-Jimenez  62 Damian Scarf  63 Oi Ling Siu  64 Dan J Stein  65 Sascha Y Struijs  66 Cristina Tomoiaga  67 Karla Patricia Valdés-García  68 Sanne van Luenen  69 Daniel V Vigo  70 Angel Y Wang  71 Reinout Wiers  72 Samuel Y S Wong  73 Ronald C Kessler  74 Ronny Bruffaerts  75 WMH-ICS collaborators
Collaborators, Affiliations

Prevalence, age-of-onset, and course of mental disorders among 72,288 first-year university students from 18 countries in the World Mental Health International College Student (WMH-ICS) initiative

Andre Mason et al. J Psychiatr Res. 2025 Mar.

Abstract

Background: The college years are a developmentally sensitive period for mental disorder onset. Reliable epidemiological data are critical for informing public health responses. This study aimed to estimate prevalence and socio-demographic distributions of common DSM-5 mental disorders among first-year university students from 77 universities across 18 countries.

Methods: Data were collected 2017-2023 in the World Mental Health International College Student Initiative with n = 72,288 university students. Online surveys assessed alcohol use, attention-deficit/hyperactivity, bipolar, drug use, generalized anxiety, major depression, panic, and post-traumatic stress disorders with validated screening scales. Socio-demographics included student age, sex at birth, gender modality, sexual orientation, and parent education.

Results: The weighted mean response rate was 20.8%. Data were calibrated for differential response rates by sex at birth and age. 65.2% of respondents screened positive for lifetime mental disorders and 57.4% for 12-month mental disorders. Females had higher prevalence of internalizing disorders and males of substance and attention-deficit/hyperactivity disorders. Older age was associated with lower prevalence of most 12-month but not lifetime mental disorders. Non-heterosexual sexual orientation and identifying as transgender were associated with highest prevalence of most mental disorders. Parent education was for the most part uncorrelated with prevalence.

Conclusions: Although prevalence might have been overestimated due to the low response rate and possible screening scale miscalibration, results nonetheless suggest that mental disorders are highly prevalent among first-year university students worldwide and are widely distributed with respect to socio-demographic characteristics. These findings highlight the need to implement effective interventions to better support first-year university student mental health.

Keywords: College students; Mental disorders; WMH-ICS.

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Conflict of interest statement

Declaration of competing interest AM acknowledges that research was conducted during tenure of a Health Sciences Career Development Award of the Ōtākou Whakaihu Waka - University of Otago. In the past 3 years, RPA has received payment and stock options from Get Sonar, Inc. CA, MB. CB reports funding from the National Institute of Health (US), awarded to the National Institute of Psychiatry Ramon de la Fuente Muñiz, with Benjet as PI. AHB received funding for this work from the Swedish Research Council (ID, 2019–01127) as well as from a Public Health Agency in Sweden (ID 04252-2021-2.3.2), and has served as a consultant for National Board of Health and Welfare (Sweden), received financial support for conference participation from Karolinska Institutet, royalties from Gothia Fortbildning, relating to textbooks on addiction and crime, and has served as President of International Society of Behavioral Medicine (isbm.info). DD received grants from Research Grants Council (RGC) (Hong Kong); Health and Medical Research Fund; Save the Children Hong Kong and Merck & Co. Inc. and has served as a board member for several rare disease advocacy groups in Asia. DDE has served as a consultant to/on the scientific advisory boards of Sanofi, Novartis, Minddistrict, Lantern, Schoen Kliniken, Ideamed and German health insurance companies (BARMER, Techniker Krankenkasse) and a number of federal chambers for psychotherapy and is shareholder of GET.ON Institute/HelloBetter a provider of digital mental health care products and services. In Chile the study was funded by ANID-Millennium Science Initiative Program-NCS2021_081 and ANID/FONDECYT 1221230. JMH reports grant funding from Eli Lily & Co. and consulting fees from Otsuka. XH has received grants from Sexual Violence Research Institute, Volkswagen Foundation, Wellspring Philanthropies, Foreign, Commonwealth and Development Office (UK government), PANDA Holding Limited, National Research Foundation of South Africa, Center for Inclusive Policy. XH reports consulting fees from Mastercard Foundation, Missing Billion Initiative, UNICEF, International Food Policy Research Institute and the African Union. Hunt has received funding support to attend conferences from Mastercard Foundation and Charité University (Germany). PH has received funding for this work from Suicide Prevention Australia, the Feilman Foundation, and the National Health and Medical Research Council (ID, 2032058). MH reports consulting fees from Child Mind Institute, New York. AMK has received lecture fees for mental health workshops and presentations for German statutory health insurance company, Techniker Krankenkasse. YL received grant support from Taishan Scholars Program of Shandong Province. AM acknowledges that research was conducted during tenure of a Health Sciences Career Development Award of the Ōtākou Whakaihu Waka - University of Otago. DJS reports personal fees from Discovery Vitality, Johnson & Johnson, Kanna, L'Oreal, Lundbeck, Orion, Sanofi, Servier, Takeda and Vistagen. DVV reports grant support from Health Canada, Canadian Institutes for Health Research, Provincial Health Services Authority and an internal research grant from the University of British Columbia. The BC Ministry of Health and the Department of Interior Health made payments to Dr. Vigo with respect to contracts for projects related to mental health service provision. RW received lecture fees for presentations from Clinical Psychology Training, The Netherlands. In the past 3 years, RCK was a consultant for Cambridge Health Alliance, Canandaigua VA Medical Center, Child Mind Institute, Holmusk, Massachusetts General Hospital, Partners Healthcare, Inc., RallyPoint Networks, Inc., Sage Therapeutics and University of North Carolina. He has stock options in Cerebral Inc., Mirah, PYM (Prepare Your Mind), Roga Sciences and Verisense Health.

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