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. 2025 Feb 25;10(2):e016880.
doi: 10.1136/bmjgh-2024-016880.

A health systems approach to more effective decentralised HIV prevention: development of Malawi's Blantyre Prevention Strategy

Affiliations

A health systems approach to more effective decentralised HIV prevention: development of Malawi's Blantyre Prevention Strategy

Gift Kawalazira et al. BMJ Glob Health. .

Abstract

Achieving global targets to end the HIV/AIDS epidemic as a public health threat by 2030 and beyond requires enhanced health system capacity for HIV prevention at national and subnational levels. Specifically, this system's capacity must enable countries to reach high-risk populations effectively, systematically engage communities to generate demand for HIV prevention services, build diverse delivery channels to meet this demand and address structural barriers that undermine prevention programmes. Integrating these capacities at the local level is especially critical to creating sustainable uptake and impact of emerging highly efficacious prevention options, such as long-acting injectable pre-exposure prophylaxis. Decentralised, locally led approaches that reflect the local context-yet are linked to national systems and policies-are needed to embed these capacities and strengthen the ability of local governments to coordinate and implement HIV prevention. Within this framework, the Government of Malawi is developing a district-based approach to enhance local institutional capacity for more effective and sustainable HIV prevention, starting in Blantyre-a large urban district noted for its high HIV incidence. This article provides the conceptual basis for, and early implementation experience of, the Blantyre Prevention Strategy (BPS), a health systems-based approach to HIV prevention that directs investments towards embedding essential functions within Blantyre City and District. The approach includes developing district-led systems and capabilities in effective disease surveillance and data-driven targeting, demand generation, quality service delivery and promoting the sustained use of HIV prevention interventions. Early learnings from BPS offer lessons for other low- and middle-income countries seeking to implement HIV prevention strategies that bolster their health system capacity and integrate with broader health responses.

Keywords: AIDS; HIV; Health policy; Prevention strategies; Public Health.

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Conflict of interest statement

Competing interests: CBH declares: (a) a grant from the Bill & Melinda Gates Foundation (BMGF) to the Center for Innovation in Global Health (CIGH) at Georgetown for the Blantyre Prevention Strategy (BPS); (b) consulting with the Bill and Melinda Gates Medical Research Institute for work unrelated to the manuscript and (c) membership on the board of directors for the Center for Infectious Diseases Research in Zambia (CIDRZ). SMA declares: (a) funding support from BMGF for BPS; (b) consulting fees and grants from Pharos Global Health Advisors and (c) participation on a data safety monitoring/advisory board in the form of the MOSAIC Product Access Advisory Committee (PAAC) (Family Health International). DH and BOI declare: (a) funding support from BMGF for BPS. TS declares: (a) funding from CIGH for technical support for BPS and (b) funding support from BMGF through Kuunika and BPS.

Figures

Figure 1
Figure 1. Establishing a virtuous cycle of health systems change through the establishment of core functions and key enablers of strengthened district-based prevention through BPS. BPS, Blantyre Prevention Strategy.

References

    1. Matchaya G. Trends in life expectancy and the macroeconomy in Malawi. Malawi Med J. 2007;19:154–8. doi: 10.4314/mmj.v19i4.10946. - DOI - PMC - PubMed
    1. PEPFAR Malawi country operational plan 2022 strategic direction summary. 2022 https://www.state.gov/wp-content/uploads/2022/09/Malawi-COP22-SDS.pdf Available.
    1. Kim E, Jonnalagadda S, Cuervo-Rojas J, et al. Toward elimination of mother-to-child transmission of HIV in Malawi: Findings from the Malawi Population-based HIV Impact Assessment (2015-2016) PLoS One. 2022;17:e0273639. doi: 10.1371/journal.pone.0273639. - DOI - PMC - PubMed
    1. Ministry of Health Malawi . Lilongwe, Malawi: Ministry of Health; 2022. Malawi population-based hiv impact assessment 2020–2021: mphia 2020–2021. final report.https://phia.icap.columbia.edu/wp-content/uploads/2022/12/241122_Mphia_F... Available.
    1. ICAP Second population survey assessing HIV in malawi shows progress toward epidemic control. 2022. [7-May-2024]. https://phia.icap.columbia.edu/second-population-survey-assessing-hiv-in... Available. Accessed.

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