De-risking transformative microscopy technologies for broad adoption
- PMID: 40013479
- DOI: 10.1111/jmi.13400
De-risking transformative microscopy technologies for broad adoption
Abstract
The past 20 years have seen a paradigm-shifting explosion of new optical microscopy technologies aimed at uncovering fundamental biological insights. Yet only a small portion 'cross the finish line' into wide adoption by the life science community. We contend that this is not primarily due to a lack of technical prowess or utility. Rather, many risks can conspire to derail the adoption of potentially disruptive technologies. One way to address these challenges is to de-risk paradigm-shifting inventions within open-access technology incubators. Here we detail the framework needed to shepherd innovative microscopy techniques through the often-treacherous adoption landscape to enable transformative scientific output.
Keywords: microscopy development; microscopy dissemination; technology de-risking; technology validation.
© 2025 Royal Microscopical Society.
References
REFERENCES
-
- Marques, G., Pengo, T., & Sanders, M. (2020). Imaging methods are vastly underreported in biomedical research. Elife, 9, e55133.
-
- Chew, T.‐L., George, R., Soell, A., & Betzig, E. (2017). Opening a path to commercialization. Optics & Photonics News, 28, 42–49.
-
- Hohlbein, J., Diederich, B., Marsikova, B., Reynaud, E. G., Holden, S., Jahr, W., Haase, R., & Prakash, K. (2022). Open microscopy in the life sciences: Quo vadis? Nature Methods, 19, 1020–1025.
-
- Cartwright, H. N., Hobson, C. M., Chew, T.‐L., Reiche, M. A., & Aaron, J. S. (2024). The challenges and opportunities of open‐access microscopy facilities. Journal of Microscopy, 294, 386–396.
-
- Lemon, W. C., & McDole, K. (2020). Live‐cell imaging in the era of too many microscopes. Current Opinion in Cell Biology, 66, 34–42.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Miscellaneous