Could the anti-modified protein antibody concept help better define seronegative rheumatoid arthritis?

Affiliations

¹ Department of Rheumatology & CIC-CRB 1404, Inserm, PANTHER UMR 1234, University of Rouen Normandie, Normandie University, CHU Rouen, 76000 Rouen, France. Electronic address: pauline.brevet@chu-rouen.fr.
² Department of Rheumatology & CIC-CRB 1404, Inserm, PANTHER UMR 1234, University of Rouen Normandie, Normandie University, CHU Rouen, 76000 Rouen, France.
³ Department of Pharmacy, UNICAEN, Inserm, ANTICIPE U1086, University of Caen Normandie, CHU Rouen, 76000 Rouen, France.
⁴ Department of Immunology and Biotherapies, Inserm, PANTHER UMR 1234, University of Rouen Normandie, Normandie University, CHU Rouen, 76000 Rouen, France.

Editorial

Pauline Brevet et al. Joint Bone Spine. 2025 Oct.

. 2025 Oct;92(5):105869.

doi: 10.1016/j.jbspin.2025.105869. Epub 2025 Feb 25.

¹ Department of Rheumatology & CIC-CRB 1404, Inserm, PANTHER UMR 1234, University of Rouen Normandie, Normandie University, CHU Rouen, 76000 Rouen, France. Electronic address: pauline.brevet@chu-rouen.fr.
² Department of Rheumatology & CIC-CRB 1404, Inserm, PANTHER UMR 1234, University of Rouen Normandie, Normandie University, CHU Rouen, 76000 Rouen, France.
³ Department of Pharmacy, UNICAEN, Inserm, ANTICIPE U1086, University of Caen Normandie, CHU Rouen, 76000 Rouen, France.
⁴ Department of Immunology and Biotherapies, Inserm, PANTHER UMR 1234, University of Rouen Normandie, Normandie University, CHU Rouen, 76000 Rouen, France.

No abstract available

Keywords: ACPA; AMPA; Anti-CarP; Autoantibodies; Seronegative rheumatoid arthritis.

Conflict of interest statement

Disclosure of interest The authors declare that they have no competing interest.