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Observational Study
. 2025 Sep;107(7):503-510.
doi: 10.1308/rcsann.2024.0096. Epub 2025 Feb 28.

Meatal stenosis and lichen sclerosus in children: is it a real risk? A single-centre retrospective observational study

R Angotti  1 , F Nascimben  1 , M Messina  1 , A Roggero  1 , N Calomino  1 , V Bagnara  2 , F Raffaelli  1 , F Ferrara  1 , A Benigna  1 , F Molinaro  1
Affiliations
Observational Study

Meatal stenosis and lichen sclerosus in children: is it a real risk? A single-centre retrospective observational study

R Angotti et al. Ann R Coll Surg Engl. 2025 Sep.

Abstract

Background: Early diagnosis, early treatment and long-term follow-up in paediatric patients with Lichen Sclerosus (LS) are mandatory to avoid complications such as urethral meatal stenosis.

Methods: All patients older than five years who underwent circumcision from January 2015 to December 2021 at our centre with positive histology for LS were included. Demographic, preoperative, surgical and postoperative data were analysed. Patients were physically evaluated, and they were asked to fill in two quality of life questionnaires and to perform an uroflowmetry. They were stratified into clusters according to physical and histological examination. Urethral dilatations were investigated to assess the correlation between circumcision and incidence of LS-linked complications.

Results: Among 99 patients included in the study, 95 were finally evaluated. Median age at diagnosis was seven years (range, five to ten years). Median age at surgery was 10.8 years (6-17). Urethral meatus was grade 0 in 47% of cases, grade 1 in 41% and grade 2 in 12%. A total of 19% of circumcised patients with LS had pathological uroflowmetry: the number of patients with pathological uroflowmetry increased as the grade of meatal stenosis increased (13% grade 0, 15% grade 1 and 33% grade 2). Four (4.7%) patients with diagnosis of meatal stenosis underwent meatal dilatations.

Conclusions: By assessing histology of LS it is possible to determine who will develop LS-linked complications such as meatal stenosis. Patients with LS must be followed-up closely and should be treated with corticosteroids for at least for one month to improve their postoperative outcomes.

Keywords: Children; Circumcision; Lichen Sclerosus; Meatal stenosis; Phimosis.

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Figures

Figure 1
Figure 1
Penile perception score (PPS)
Figure 2
Figure 2
(A) PedsQL parent report. (B) PedsQL child report. PedsQL = Pediatric Quality of Life Inventory.
Figure 2
Figure 2
(A) PedsQL parent report. (B) PedsQL child report. PedsQL = Pediatric Quality of Life Inventory.
Figure 3
Figure 3
Paediatric penile perception score—patients and surgeon
Figure 4
Figure 4
Paediatric penile perception score – patients and parents
Figure 5
Figure 5
PedsQL – correlation between patients and parents
Figure 6
Figure 6
Correlation between postoperative corticosteroid topical therapy and the results of uroflowmetry based on meatal stenosis grade
See this image and copyright information in PMC

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