What Can We Learn from Differences in Hospitals' Sepsis Care?

Michael Klompas^{1

2}, Mitchell M Levy³

Affiliations

¹ Department of Population Medicine Harvard Medical School and Harvard Pilgrim Health Care Institute Boston, Massachusetts.
² Department of Medicine Brigham and Women's Hospital Boston, Massachusetts.
³ Division of Pulmonary, Critical Care and Sleep Medicine The Warren Alpert Medical School of Brown University Providence, Rhode Island.

Editorial

Michael Klompas et al. Am J Respir Crit Care Med. 2025 Apr.

. 2025 Apr;211(4):546-547.

doi: 10.1164/rccm.202501-0106ED.

Michael Klompas^{1

2}, Mitchell M Levy³

¹ Department of Population Medicine Harvard Medical School and Harvard Pilgrim Health Care Institute Boston, Massachusetts.
² Department of Medicine Brigham and Women's Hospital Boston, Massachusetts.
³ Division of Pulmonary, Critical Care and Sleep Medicine The Warren Alpert Medical School of Brown University Providence, Rhode Island.

No abstract available

Comment on

Status of Sepsis Care in European Hospitals: Results from an International Cross-Sectional Survey.
Scheer CS, Giamarellos-Bourboulis EJ, Ferrer R, Idelevich EA, Annane D, Artigas A, Aslan AT, Bottari G, Bouma HR, Černý V, Curić Radivojević R, Dakou K, Dewitte K, Elbahnasawy M, Gründling M, Gurjar M, Hästbacka J, Kyprianou M, Laribi S, Lassen A, Lebedinskii K, Máca J, Malbrain MLNG, Monti G, Ostermann M, Osthoff M, Paiva JA, Sabbatucci M, Śmiechowicz J, Ştefan MG, Vollmer M, Vuković N, Zaragkoulias K, Reinhart K, Linder A, Filipescu D; European Sepsis Care Study Group. Scheer CS, et al. Am J Respir Crit Care Med. 2025 Apr;211(4):587-599. doi: 10.1164/rccm.202406-1167OC. Am J Respir Crit Care Med. 2025. PMID: 39787606 Free PMC article.

1. Rudd KE, Johnson SC, Agesa KM, Shackelford KA, Tsoi D, Kievlan DR, et al. Global, regional, and national sepsis incidence and mortality, 1990-2017: analysis for the Global Burden of Disease Study. Lancet . 2020;395:200–211. - PMC - PubMed
1. Scheer CS, Giamarellos-Bourboulis EJ, Ferrer R, Idelevich EA, Annane D, Artigas A, et al. European Sepsis Care Study Group Status of sepsis care in European hospitals: results from an international cross-sectional survey. Am J Respir Crit Care Med . 2025;211:587–599. - PMC - PubMed
1. Centers for Disease Control and Prevention (CDC) Atlanta, GA: CDC; 2024. Hospital sepsis management and practices: findings from the 2023 National Healthcare Safety Network Patient Safety Component Annual Survey.www.cdc.gov/sepsis/media/pdfs/hospital-2023-annual-survey-508.pdf
1. Townsend SR, Phillips GS, Duseja R, Tefera L, Cruikshank D, Dickerson R, et al. Effects of compliance with the early management bundle (SEP-1) on mortality changes among Medicare beneficiaries with sepsis: a propensity score matched cohort study. Chest . 2022;161:392–406. - PubMed
1. Barbash IJ, Davis BS, Yabes JG, Seymour CW, Angus DC, Kahn JM. Treatment patterns and clinical outcomes after the introduction of the Medicare sepsis performance measure (SEP-1) Ann Intern Med . 2021;174:927–935. - PMC - PubMed