Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 May:189:109858.
doi: 10.1016/j.compbiomed.2025.109858. Epub 2025 Feb 27.

Deep learning-driven prediction in healthcare systems: Applying advanced CNNs for enhanced breast cancer detection

Affiliations

Deep learning-driven prediction in healthcare systems: Applying advanced CNNs for enhanced breast cancer detection

Marouene Chaieb et al. Comput Biol Med. 2025 May.

Abstract

The mortality risk associated with breast cancer is experiencing an exponential rise, underscoring the critical importance of early detection. It is the primary cause of mortality among women under 50 and ranks as the second deadliest disease globally. Timely identification is crucial, as heightened public awareness and accurate diagnosis can significantly reduce mortality rates. Patients with a positive prognosis and timely diagnosis have a far greater chance of full recovery. A comprehensive study was conducted to develop a robust breast cancer detection system using Convolutional Neural Networks (CNNs). This study details the processes of data collection, preprocessing, model building, and performance evaluation. The Mini-DDSM dataset was utilized, which includes 1952 scanned film mammograms from a diverse population. Data preprocessing involved normalization, denoising, illumination correction, and augmentation techniques to enhance data quality and diversity. During the model-building stage, several CNN architectures were explored, including Basic CNN, FT-VGG19, FT-ResNet152, and FT-ResNet50. The FT-ResNet50 model, fine-tuned with transfer learning, emerged as the top performer, achieving an accuracy of 97.54%. The integrated system leverages the strengths of each model to deliver accurate and reliable results, significantly advancing early detection and treatment methods for breast cancer. The comparative analysis demonstrated that the developed models outperformed existing state-of-the-art models. By leveraging the capabilities of deep learning and meticulous design, the objective is to significantly advance early detection and treatment methods for breast cancer, leading to better patient outcomes and ultimately, saving lives.

Keywords: Breast cancer; Convolutional Neural Networks; Deep learning; Fine tuning; Mammography classification; Transfer learning.

PubMed Disclaimer

Conflict of interest statement

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

LinkOut - more resources