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Case Reports
. 2025 Mar;31(3):617-619.
doi: 10.3201/eid3103.241361.

Neurosarcocystosis in Patient with HIV-Induced Immunodeficiency

Tonje Skarpengland, Anders A Tveita, Christopher F Berntsen, Erik E Christensen, Magnhild E Macpherson, Birgitte Stiksrud, Nils O Hermansen, Pitt Niehusmann, Tine S Oldereid, Espen Stjernstrøm, Hanne Brekke, Henrik V Nielsen, Frank O D Pettersen
Case Reports

Neurosarcocystosis in Patient with HIV-Induced Immunodeficiency

Tonje Skarpengland et al. Emerg Infect Dis. 2025 Mar.

Abstract

Sarcocystis is a genus of protozoan parasites that can infect various vertebrates. In humans, Sarcocystis infection usually is asymptomatic but might manifest as a mild gastroenteritis or extraintestinal myositis. We report a case of human central nervous system infection in Norway caused by S. nesbitti parasites.

Keywords: HIV; Norway; S. nesbitti; Sarcocystis; Thailand; molecular diagnostic; opportunistic infection; parasites; sarcocystosis; zoonoses.

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Figures

Figure
Figure
Microscopic findings and imaging results for patient with HIV-induced immunodeficiency preceding diagnosis of neurosarcocystosis, Norway. A) Light microscopic findings of structures resembling Toxoplasma gondii bradozoites (white arrows) in brain biopsy. Hematoxylin and eosin stain. Scale bars of enlarged images indicate 50 μm; scale bar of background image indicates 100 μm. B) Magnetic resonance imaging of cerebral and spinal cord lesions (contrast enhanced sagtittal T1 sequence, left panel, red arrows) and cerebral lesions with slight peripheral ring enhancement (contrast enhanced transversal T1 sequence, right panel, red arrows).
See this image and copyright information in PMC

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