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. 2025 Mar 2;22(1):28.
doi: 10.1186/s12981-025-00721-z.

Brief communication: attitudes and preferences of long-acting injectable HIV preexposure prophylaxis among Thai adolescents and young adults

Alisa Wongsethanatada  1 , Wipaporn Natalie Songtaweesin  2   3 , Prissana Wongharn  4 , Juthamanee Moonwong  4 , Sasiprapha Khamthi  4 , Lucksanapon Pitikawinwong  4 , Thanyawee Puthanakit  4   5   6
Affiliations

Brief communication: attitudes and preferences of long-acting injectable HIV preexposure prophylaxis among Thai adolescents and young adults

Alisa Wongsethanatada et al. AIDS Res Ther. .

Abstract

This study aimed to explore willingness to use and preference for long-acting injectable PrEP (LAI-PrEP) among Thai youth at risk of HIV. A cross-sectional study was conducted in 100 Thai youth aged 18 to 24 years attending a sexual health clinic in Bangkok, Thailand. Participants received information about oral and LAI-PrEP before completing a questionnaire. Of the 98 participants willing to use pre-exposure prophylaxis, 47 preferred the injectable form. Preference for the injectable form was higher among individuals not currently using oral pre-exposure prophylaxis, affordability and longer injection intervals were key for acceptance of long-acting injectable pre-exposure prophylaxis.

Keywords: Adolescents; HIV; Long-acting; Men who have sex with men; PrEP; Preference; Youth.

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Conflict of interest statement

Declarations. Ethics approval and consent to participate: This study was approved by the Institutional Review Board of the Faculty of Medicine, Chulalongkorn University, and all participants provided informed consent before participating in the study. Consent for publication: All authors have reviewed and approved the manuscript for publication. No individual participant data is included that requires additional consent. The study abstract has been presented at the International Workshop on Pediatrics & HIV, Munich, July 2024, eposter number 189. Competing interests: The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Willingness to use long-acting PrEP at different injection intervals among active PrEP users and non-PrEP users*. Abbreviations: PrEP, Pre-Exposure Prophylaxis. *non-PrEP users refers to former oral PrEP users and those who had never used PrEP before, PrEP users refers to active oral PrEP users
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