Adherence patterns and their determinants among oral isotretinoin initiators

C Payet^{1

2}, V Fernandez^{1

2}, A Moskal^{1

2}, M Chanelière^{1

3}, B Lebrun-Vignes⁴, A Dima⁵, M Viprey^{1

2}

Affiliations

¹ Research on Healthcare Performance (RESHAPE), INSERM U1290, Université Claude Bernard Lyon 1, Lyon, France.
² Service des Données de Santé, Hospices Civils de Lyon, Lyon, France.
³ Collège Universitaire de Médecine Générale, Université Lyon 1, Villeurbanne, France.
⁴ Service de Pharmacologie, Centre Régional de Pharmacovigilance, Hôpital Pitié-Salpêtrière, AP-HP, GH Sorbonne Université, Paris, France.
⁵ Institut Universitaire Avedis Donabedian, Université Autonome de Barcelone, Espagne.

C Payet et al. J Eur Acad Dermatol Venereol. 2025 Oct.

. 2025 Oct;39(10):e889-e892.

doi: 10.1111/jdv.20627. Epub 2025 Mar 3.

C Payet^{1

2}, V Fernandez^{1

2}, A Moskal^{1

2}, M Chanelière^{1

3}, B Lebrun-Vignes⁴, A Dima⁵, M Viprey^{1

2}

¹ Research on Healthcare Performance (RESHAPE), INSERM U1290, Université Claude Bernard Lyon 1, Lyon, France.
² Service des Données de Santé, Hospices Civils de Lyon, Lyon, France.
³ Collège Universitaire de Médecine Générale, Université Lyon 1, Villeurbanne, France.
⁴ Service de Pharmacologie, Centre Régional de Pharmacovigilance, Hôpital Pitié-Salpêtrière, AP-HP, GH Sorbonne Université, Paris, France.
⁵ Institut Universitaire Avedis Donabedian, Université Autonome de Barcelone, Espagne.

No abstract available

References

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1. Layton AM, Dreno B, Gollnick HPM, Zouboulis CC. A review of the European directive for prescribing systemic isotretinoin for acne vulgaris. J Eur Acad Dermatol Venereol. 2006;20:773–776.
1. Havet A, Bouvard C, Moskal A, Chanelière M, Massardier J, Lebrun‐Vignes B, et al. Compliance with the pregnancy prevention program among women initiating isotretinoin treatment between 2014 and 2021: a nationwide cohort study on the French health data system (SNDS). J Eur Acad Dermatol Venereol. 2025;39:806–814. https://doi.org/10.1111/jdv.20073
1. Biset N, Lelubre M, Senterre C, Amighi K, Bugnon O, Schneider M, et al. Assessment of medication adherence and responsible use of isotretinoin and contraception through Belgian community pharmacies by using pharmacy refill data. Patient Prefer Adherence. 2018;12:153–161.
1. Dréno B, Thiboutot D, Gollnick H, Finlay AY, Layton A, Leyden JJ, et al. Large‐scale worldwide observational study of adherence with acne therapy. Int J Dermatol. 2010;49:448–456.