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Case Reports
. 2023 Oct 1;2(4):88149.
doi: 10.56305/001c.88149. eCollection 2023.

Fever of Unknown Origin and Cluster Headache: A COVID-19 Conundrum

Kavadisseril Vivekanandan Vysakha  1 , Raina Thankappan Pillai  2 , Mathew Cyriac  2 , P N Sylaja  3 , R Aravind  4
Affiliations
Case Reports

Fever of Unknown Origin and Cluster Headache: A COVID-19 Conundrum

Kavadisseril Vivekanandan Vysakha et al. J Brown Hosp Med. .

Abstract

We present a young girl with a family history of GPA who presented with fever of unknown origin and subsequently developed a secondary cluster headache. We hypothesize that the clinical manifestations are likely associated with hypothalamic dysregulation as a consequence of post-acute sequelae of COVID-19. Notably, the patient showed clinical improvement following the commencement of corticosteroid treatment.

Keywords: COVID-19; Cluster headache; FUO; SARS-CoV-2; Trigeminal autonomic cephalgia; fever of unknown origin.

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Conflict of interest statement

The authors have no conflicts of interest to disclose.

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