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. 2025 May 1;47(5):358-360.
doi: 10.1097/DAD.0000000000002951. Epub 2025 Feb 25.

Rosuvastatin Is Associated With Incidental Dermal Calcification

Affiliations

Rosuvastatin Is Associated With Incidental Dermal Calcification

Joyce B Kang et al. Am J Dermatopathol. .
No abstract available

Keywords: Mohs micrographic surgery; calcification; dermatopathology; statins.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

FIGURE 1.
FIGURE 1.
Histological image of example dermal calcium deposits. Hematoxylin and eosin–stained section from a skin biopsy obtained during Mohs surgery, showing the presence of calcifications (dark purple areas indicated by the black arrow). Samples were classified as positive for calcification only when calcium deposits were observed in the absence of any adjacent tumor, as in this example.
FIGURE 2.
FIGURE 2.
Association between the presence of calcifications and statin use, controlling for patient and sample-level variables. OR derived from logistic regression with 95% confidence interval and Wald P-values are shown. For categorical variables, the reference group is denoted with a dash. Age and defect area were Z-score normalized (min and max listed in square brackets). Red asterisks denote significant associations at 0.05 level. In plot (right), the size of the square denotes number of samples.

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