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Editorial
. 2025 Jun;27(6):979-981.
doi: 10.1002/ejhf.3628. Epub 2025 Mar 4.

If a patient does not require treatment with loop diuretics, do they really have heart failure?

John G F Cleland  1 , Jocelyn Friday  2 , Antonio Iaconelli  1   3 , Narinder Kaur  1 , Pierpaolo Pellicori  1
Affiliations
Editorial

If a patient does not require treatment with loop diuretics, do they really have heart failure?

John G F Cleland et al. Eur J Heart Fail. 2025 Jun.
No abstract available

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References

    1. Cleland JG, Tavazzi L, Daubert JC, Tageldien A, Freemantle N. Cardiac resynchronization therapy: Are modern myths preventing appropriate use? J Am Coll Cardiol 2009;53:608–611. https://doi.org/10.1016/j.jacc.2008.10.040
    1. Cleland JGF. Nature and magnitude of the benefits of dapagliflozin and empagliflozin for heart failure. Circulation 2024;149:839–842. https://doi.org/10.1161/CIRCULATIONAHA.123.068089
    1. Chouairi F, Fudim M, Savarese G, Szabo B, Dahlstrom U, Hage C, et al. Utility of loop diuretics as a marker of risk in clinical trials of heart failure with preserved ejection fraction: Analysis from the Swedish Heart Failure Registry. Eur J Heart Fail 2025;27:972–978. https://doi.org/10.1002/ejhf.3578
    1. Cleland JGF, Pfeffer MA, Clark AL, Januzzi JL, McMurray JJV, Mueller C, et al. The struggle towards a universal definition of heart failure – how to proceed? Eur Heart J 2021;42:2331–2343. https://doi.org/10.1093/eurheartj/ehab082
    1. Pellicori P, Cleland JG, Zhang J, Kallvikbacka‐Bennett A, Urbinati A, Shah P, et al. Cardiac dysfunction, congestion and loop diuretics: Their relationship to prognosis in heart failure. Cardiovasc Drugs Ther 2016;30:599–609. https://doi.org/10.1007/s10557‐016‐6697‐7

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