. 2025 Feb 17:2025:10.17912/micropub.biology.000888.
doi: 10.17912/micropub.biology.000888.
eCollection 2025.
Gene model for the ortholog of mts in Drosophila mojavensis
Affiliations
- PMID: 40041767
- PMCID: PMC11877148
- DOI: 10.17912/micropub.biology.000888
Item in Clipboard
Gene model for the ortholog of mts in Drosophila mojavensis
MicroPubl Biol.
.
Abstract
Gene model for the ortholog of microtubule star ( mts ) in the D. mojavensis May 2011 (Agencourt dmoj_caf1/DmojCAF1) Genome Assembly (GenBank Accession: GCA_000005175.1 ) of Drosophila mojavensis . This ortholog was characterized as part of a developing dataset to study the evolution of the Insulin/insulin-like growth factor signaling pathway (IIS) across the genus Drosophila using the Genomics Education Partnership gene annotation protocol for Course-based Undergraduate Research Experiences.
Copyright: © 2025 by the authors.
Conflict of interest statement
The authors declare that there are no conflicts of interest present.
Figures
(A) Synteny of genomic neighborhood of
mts
in
D. melanogaster
and
D. mojavensis
. Gene arrows pointing in the same direction as reference gene in both
D. mojavensis
and
D. melanogaster
are on the same strand as the reference gene; gene arrows pointing in the opposite direction are on the opposite strand. The thin underlying arrows pointing to the right indicate that
mts
is on the + strand; arrows pointing to the left indicate that
mts
is on the – strands. Arrows in
D. mojavensis
indicate the locus ID of the genes, white arrows indicate orthology to the corresponding gene in
D. melanogaster
, gray arrows indicate an orthologous gene pointing in the opposite direction as
D. melanogaster
relative to
mts
, and black arrows indicate a non-orthologous gene. The gene names given in the
D. mojavensis
gene arrows indicate the orthologous gene in
D. melanogaster
, while the locus identifiers are specific to
D. mojavensis
.
(B) Gene Model in UCSC Track Hub (Raney et al. 2014): the gene model in
D. mojavensis
(black), Spaln of
D. melanogaster
Proteins (purple, alignment of RefSeq proteins from
D. melanogaster
), BLAT alignments of NCBI RefSeq Genes (blue, alignment of RefSeq genes for
D. mojavensis
), RNA-Seq from adult females (red) and adult males (blue) (alignment of Illumina RNA-Seq reads from
D. mojavensis
), and Transcripts (green) including coding regions predicted by TransDecoder and Splice Junctions Predicted by regtools using
D. mojavensis
RNA-Seq (Chen
et al.
,
2014;
SRP006203
). Splice junctions shown have a minimum read-depth of 1362 with >1000 supporting reads shown in red. The custom gene model (User Supplied Track) is indicated in black with CDSs depicted with boxes and introns with narrow lines (arrows indicate direction of transcription). (C) Dot Plot of mts_PA in
D. melanogaster
(
x
-axis) vs. the orthologous peptide in
D. mojavensis
(
y
-axis). Amino acid number is indicated along the left and bottom; CDS number is indicated along the top and right, and CDSs are also highlighted with alternating colors.
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