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Editorial
. 2025 Mar 5;40(3):ivaf056.
doi: 10.1093/icvts/ivaf056.

Rethinking the pathophysiology of Fontan circulation: insights from Kenji Sunagawa and Arthur Guyton

Loïc Georges Macé  1   2 , Marien Lenoir  1   2
Affiliations
Editorial

Rethinking the pathophysiology of Fontan circulation: insights from Kenji Sunagawa and Arthur Guyton

Loïc Georges Macé et al. Interdiscip Cardiovasc Thorac Surg. .
No abstract available

Keywords: Fontan operation; physiology; univentricular heart; venous return; ventricular-vascular coupling; ventriculo-arterial coupling.

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Comment in

  • Reply to Macé et al.
    Van Puyvelde J, Rega F, Meyns B. Van Puyvelde J, et al. Interdiscip Cardiovasc Thorac Surg. 2025 Mar 5;40(3):ivaf058. doi: 10.1093/icvts/ivaf058. Interdiscip Cardiovasc Thorac Surg. 2025. PMID: 40080697 Free PMC article. No abstract available.

Comment on

  • Defining the causes for Fontan circulatory failure in total cavopulmonary connection patients.
    Van Puyvelde J, Rega F, Budts W, Van De Bruaene A, Cools B, Gewillig M, Eyskens B, Heying R, Salaets T, Meyns B. Van Puyvelde J, et al. Interdiscip Cardiovasc Thorac Surg. 2024 Nov 6;39(5):ivae188. doi: 10.1093/icvts/ivae188. Interdiscip Cardiovasc Thorac Surg. 2024. PMID: 39565923 Free PMC article.
  • Reply to Macé et al.
    Van Puyvelde J, Rega F, Meyns B. Van Puyvelde J, et al. Interdiscip Cardiovasc Thorac Surg. 2025 Mar 5;40(3):ivaf058. doi: 10.1093/icvts/ivaf058. Interdiscip Cardiovasc Thorac Surg. 2025. PMID: 40080697 Free PMC article. No abstract available.

References

    1. Van Puyvelde J, Rega F, Budts W et al. Defining the causes for Fontan circulatory failure in total cavopulmonary connection patients. Interdiscip Cardiovasc Thorac Surg 2024;39. doi: 10.1093/icvts/ivae188. - DOI - PMC - PubMed
    1. Sunagawa K, Sagawa K, Maughan WL. Ventricular interaction with the loading system. Ann Biomed Eng 1984;12:163–89. - PubMed
    1. Szabó G, Buhmann V, Graf A et al. Ventricular energetics after the Fontan operation: contractility-afterload mismatch. J Thorac Cardiovasc Surg 2003;125:1061–9. - PubMed
    1. Redington A. The physiology of the Fontan circulation. Prog Pediatr Cardiol 2006;22:179–86.
    1. Guyton AC, Abernathy B, Langston JB, Kaufmann BN, Fairchild HM. Relative importance of venous and arterial resistances in controlling venous return and cardiac output. Am J Physiol 1959;196:1008–14. - PubMed

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