Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2025 Feb;19(2):103205.
doi: 10.1016/j.dsx.2025.103205. Epub 2025 Feb 13.

Ahmedabad declaration: A framework to combat growing epidemic of young-onset type 2 diabetes in Asia

Rakesh M Parikh  1 , Banshi Saboo  2 , Anoop Misra  3 , Abdul Basit  4 , S R Aravind  5 , Bishwajit Bhowmik  6 , Peter Schwarz  7 , Ketan Dhatariya  8 , Kamlesh Khunti  9 , Shashank Joshi  10 , Sunil Gupta  11 , Amit Gupta  12 , Manoj Chawla  13 , Sanjeev Phatak  14 , Sanjay Kalra  15 , Azad Khan  16 , Viswanathan Mohan  17 ; Ahmedabad Declaration Committee Members
Collaborators, Affiliations
Review

Ahmedabad declaration: A framework to combat growing epidemic of young-onset type 2 diabetes in Asia

Rakesh M Parikh et al. Diabetes Metab Syndr. 2025 Feb.

Abstract

Aim: Rising prevalence of Type 2 Diabetes (T2D) among young Asians has emerged as a public health crisis that threatens the long-term health, economic stability, and productivity of nations across Asia (1). Early-onset T2D poses unique challenges, including higher rates of undiagnosed cases, more aggressive disease progression, an increased risk of chronic complications and higher mortality (2). Hyperglycemia during the reproductive age especially among the female population can potentially have transgenerational impact through epigenetic changes.

Methods: A comprehensive search was conducted on PubMed with a combination of relevant keywords. A preliminary draft prepared after review of literature was electronically circulated among a panel of 64 experts from various parts of the region and representatives of the participating organizations - Diabetes India (www.diabetesindia.org.in) and the Diabetes Asia Study Group (DASG, www.da-sg.org).

Results: This Ahmedabad Declaration outlines the scale of the problem, its root causes, and a comprehensive action plan for Asian populations. The objectives of this declaration include raising awareness, addressing systemic barriers, and advocating for evidence-based policies and interventions, limited to people with T2D. Through collaborative efforts, we aim to mitigate the growing burden of diabetes in young Asians and secure a healthier future.

Keywords: Abdominal obesity; Asian; Asians; Obesity; Prevention; South Asia; Young-onset T2D.

PubMed Disclaimer

Conflict of interest statement

Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Anoop Misra reports a relationship with USV, Astra Zeneca, Eli Lilly, Lupin, Boehringer Ingelheim, Janssen, Cipla, Glenmark, Novo Nordisk that includes: funding grants, speaking and lecture fees, and travel reimbursement. Viswanathan Mohan reports a relationship with Novo Nordisk, Abbott, Sanofi, Servier, Boehringer Ingelheim, Eli Lilly, Lifescan, Roche, MSD, Novartis, Bayer, USV, Dr. Reddy's, Sun Pharma, INTAS, Lupin, Glenmark, Zydus, IPCA, Torrent, Cipla, Biocon, Primus, Franco Indian, Wockhardt, Emcure, Mankind, Medtronic, Fourrts, Apex, GSK and Alembic that includes: consulting or advisory, funding grants, and speaking and lecture fees. If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

References

    1. Ranasinghe P, Rathnayake N, Wijayawardhana S, Jeyapragasam H, Meegoda VJ, Jayawardena R, et al. Rising trends of diabetes in South Asia: a systematic review and meta-analysis. Diabetes Metabol Syndr 2024. Nov-Dec;18(11–12):103160. - PubMed
    1. Hills AP, Arena R, Khunti K, Yajnik CS, Jayawardena R, Henry CJ, et al. Epidemiology and determinants of type 2 diabetes in south Asia. Lancet Diabetes Endocrinol 2018. Dec;6(12):966–78. - PubMed
    1. Zhou Bin et al. Worldwide trends in diabetes prevalence and treatment from 1990 to 2022: a pooled analysis of 1108 population-representative studies with 141 million participants. Lancet; 404 (10467): 2077 - 2093. - PMC - PubMed
    1. Anjana RM, Unnikrishnan R, Deepa M, Pradeepa R, Tandon N, Das AK, et al. Metabolic non-communicable disease health report of India: the ICMR-INDIAB national cross-sectional study (ICMR-INDIAB-17). Lancet Diabetes Endocrinol 2023. Jul;11(7):474–89. - PubMed
    1. Anjana RM, Deepa M, Pradeepa R, Mahanta J, Narain K, Das HK, et al. Prevalence of diabetes and prediabetes in 15 states of India: results from the ICMR-INDIAB population-based cross-sectional study. Lancet Diabetes Endocrinol 2017. Aug;5 (8):585–96. - PubMed