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Editorial
. 2025 Mar 5;30(5):103110.
doi: 10.1016/j.jaccas.2024.103110.

A Kratomic Bomb: Cardiotoxicities From Mitragyna speciosa Extract

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Editorial

A Kratomic Bomb: Cardiotoxicities From Mitragyna speciosa Extract

Vardhmaan Jain et al. JACC Case Rep. .
No abstract available

Keywords: Brugada; QRS prolongation; QT prolongation; kratom; mitragynine.

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Conflict of interest statement

Funding Support and Author Disclosures The authors have reported that they have no relationships relevant to the contents of this paper to disclose.

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References

    1. Leong Bin Abdullah M.F.I., Singh D. The adverse cardiovascular effects and cardiotoxicity of kratom (Mitragyna speciosa Korth.): a comprehensive review. Front Pharmacol. 2021;12 - PMC - PubMed
    1. Miller A.H.F., Krotulski A.J., Walton S.E., et al. Kratom cardiotoxicity: reversible Brugada pattern and QTc prolongation. JACC Case Rep. 2025;30(5) - PubMed
    1. Brugada P., Brugada J. Right bundle branch block, persistent ST segment elevation and sudden cardiac death: a distinct clinical and electrocardiographic syndrome. A multicenter report. J Am Coll Cardiol. 1992;20:1391–1396. - PubMed
    1. Yap Y.G., Behr E.R., Camm A.J. Drug-induced Brugada syndrome. Europace. 2009;11:989–994. - PubMed
    1. Mizusawa Y., Wilde A.A.M. Brugada syndrome. Circ Arrhythm Electrophysiol. 2012;5:606–616. - PubMed

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