Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2025 Apr;36(2):199-205.
doi: 10.1016/j.nec.2024.12.006. Epub 2025 Feb 5.

Guidelines for Diagnosis and Management of Idiopathic Normal Pressure Hydrocephalus

Affiliations
Review

Guidelines for Diagnosis and Management of Idiopathic Normal Pressure Hydrocephalus

Mark G Hamilton et al. Neurosurg Clin N Am. 2025 Apr.

Abstract

In 1965, Hakim and Adams described 3 patients with normal pressure hydrocephalus who responded to treatment with a ventriculoatrial shunt. Afterward the adoption of shunt treatment without clear diagnostic criteria and surgical techniques resulted in poor outcomes with significant complications. The clinical practice guidelines for the diagnosis and treatment of idiopathic normal pressure hydrocephalus were first published by the Japanese Neurosurgical Society in 2004 and the international guidelines were published in 2005. Both guidelines led to diagnosis and treatment algorithms and significantly improved outcomes, along with decreased surgical risk. These guidelines should be reevaluated and updated on a regular basis.

Keywords: Clinical practice guidelines; Hydrocephalus; Idiopathic normal pressure hydrocephalus; Shunt; iNPH.

PubMed Disclaimer

Conflict of interest statement

Disclosures Dr M.G. Hamilton has received consulting fees from Integra International and CereVasc. Dr M. Tullberg has received honoraria for lecturing from Integra International and B Braun.

MeSH terms

LinkOut - more resources