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Editorial
. 2025 Apr;21(5):261-264.
doi: 10.1080/14796678.2025.2477429. Epub 2025 Mar 7.

Treatment of obesity-related HFpEF: a STEP closer to the SUMMIT

Affiliations
Editorial

Treatment of obesity-related HFpEF: a STEP closer to the SUMMIT

Paschalis Karakasis et al. Future Cardiol. 2025 Apr.
No abstract available

Keywords: Obesity; heart failure; mortality; semaglutide; tirzepatide; treatment.

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Conflict of interest statement

The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.

References

    1. NCD Risk Factor Collaboration (NCD-RisC) . Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults. Lancet. 2024;403(10431):1027–1050. doi: 10.1016/S0140-6736(23)02750-2 - DOI - PMC - PubMed
    1. Powell-Wiley TM, Poirier P, Burke LE, et al. Obesity and cardiovascular disease: a scientific statement from the American heart association. Circulation. 2021;143(21):e984–e1010. doi: 10.1161/CIR.0000000000000973 - DOI - PMC - PubMed
    1. Riaz H, Khan MS, Siddiqi TJ, et al. Association between obesity and cardiovascular outcomes: a systematic review and meta-analysis of Mendelian randomization studies. JAMA Netw Open. 2018;1(7):e183788. doi: 10.1001/jamanetworkopen.2018.3788 - DOI - PMC - PubMed
    1. Campbell P, Rutten FH, Lee MM, et al. Heart failure with preserved ejection fraction: everything the clinician needs to know. Lancet. 2024;403(10431):1083–1092. doi: 10.1016/S0140-6736(23)02756-3 - DOI - PubMed
    1. Li S, Zheng Y, Huang Y, et al. Association of body mass index and prognosis in patients with HFpEF: a dose-response meta-analysis. Int J Cardiol. 2022;361:40–46. doi: 10.1016/j.ijcard.2022.05.018 - DOI - PubMed

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