Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2025 May 1;67(5):376-384.
doi: 10.1097/JOM.0000000000003367. Epub 2025 Feb 27.

Laboratory Animal Allergy

Affiliations
Review

Laboratory Animal Allergy

Gregg M Stave et al. J Occup Environ Med. .

Abstract

Ranging from mild respiratory allergy to anaphylaxis, laboratory animal allergy (LAA) can adversely affect an individual's health and career. LAA can be prevented through a hierarchy of controls. However, workers remain at risk as many, if not most, workplaces have not fully adopted needed prevention practices. To address this risk, organizations should use a multidisciplinary leadership team. Along with participation on the leadership team, occupational medicine physicians should oversee a medical surveillance program that identifies workers with LAA including incident cases, as well as workers with LAA who are symptomatic in the workplace. One indication that medical surveillance may be effective in identifying incident cases is that it is detecting prevalent cases, usually in the range of 10%-20% or higher. Programs with lower detection rates of prevalent cases should adjust their approach to medical surveillance. The results of medical surveillance, including the incidence and prevalence of LAA, should be shared within the organization and used to guide the use of controls. Periodic self-audits are recommended to better protect workers by identifying and addressing opportunities for program improvement.

Keywords: allergens; anaphylaxis; medical surveillance; occupational asthma; self-audit; workplace health.

PubMed Disclaimer

Conflict of interest statement

Conflict of interest: GMS receives royalties from John Wiley and Sons. MDS serves as an unpaid elected director on the ACOEM Board of Directors.

References

    1. Chan SK, Leung DYM. Dog and cat allergies: current state of diagnostic approaches and challenges. Allergy Asthma Immunol Res 2018;10:97–105.
    1. Bush RK. Mechanism and epidemiology of laboratory animal allergy. ILAR J 2001;42:4–11.
    1. Bush RK, Wood RA, Eggleston PA. Laboratory animal allergy. J Allergy Clin Immunol 1998;102:99–112.
    1. Bush RK, Stave GM. Laboratory animal allergy: an update. ILAR J 2003;44:28–51.
    1. Goodno LE, Stave GM. Primary and secondary allergies to laboratory animals. J Occup Environ Med 2002;44:1143–1152.

MeSH terms