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. 2025 Jan 13:10:5.
doi: 10.12688/wellcomeopenres.23494.1. eCollection 2025.

Insights of SEDRIC, the Surveillance and Epidemiology of Drug-Resistant Infections Consortium

Nicholas Feasey  1   2 , Raheelah Ahmad  3   4   5 , Elizabeth Ashley  6 , Rifat Atun  7 , Kate S Baker  8   9 , Francesca Chiari  10 , H Rogier van Doorn  6   11 , Alison Holmes  3 , Timothy Jinks  10 , Andrew Jermy  12 , Jyoti Joshi  13 , Souha S Kanj  14 , Matt King  15 , Direk Limmathurotsakul  16 , Janet Midega  10 , Mirfin Mpundu  17 , Jamie Nunn  18 , Iruka N Okeke  19 , Stuart Reid  20 , Dawn Sievert  21 , Paul Turner  6   22 , Kamini Walia  23 , Sharon J Peacock  24
Affiliations

Insights of SEDRIC, the Surveillance and Epidemiology of Drug-Resistant Infections Consortium

Nicholas Feasey et al. Wellcome Open Res. .

Abstract

The increasing threat from infection with drug-resistant pathogens is among the most serious public health challenges of our time. Formed by Wellcome in 2018, the Surveillance and Epidemiology of Drug-Resistant Infections Consortium (SEDRIC) is an international think tank whose aim is to inform policy and change the way countries track, share, and analyse data relating to drug-resistant infections, by defining knowledge gaps and identifying barriers to the delivery of global surveillance. SEDRIC delivers its aims through discussions and analyses by world-leading scientists that result in recommendations and advocacy to Wellcome and others. As a result, SEDRIC has made key contributions in furthering global and national actions. Here, we look back at the work of the consortium between 2018-2024, highlighting notable successes. We provide specific examples where technical analyses and recommendations have helped to inform policy and funding priorities that will have real-world impact on the surveillance and epidemiology of infections with drug-resistant pathogens.

Keywords: Antimicrobial resistance; surveillance.

Plain language summary

The increasing threat from infections that cannot be treated with medicines, so called drug resistant infections, is among the most serious public health challenges of our time. Formed by Wellcome in 2018, the Surveillance and Epidemiology of Drug-Resistant Infections Consortium (SEDRIC) is an international think tank whose aim is to inform policy and change the way countries track, share, and analyse data relating to drug-resistant infections, by defining knowledge gaps and identifying barriers to the delivery of global surveillance. SEDRIC delivers its aims through discussions and analyses by world-leading scientists that result in recommendations and advocacy to Wellcome and others. As a result, SEDRIC has made key contributions in furthering global and national actions. Here, we look back at the work of the consortium between 2018-2024, highlighting notable successes. We provide specific examples where technical analyses and recommendations have helped to inform policy and funding priorities that will have real-world impact on the surveillance and of infections with pathogens that are becoming difficult or impossible to treat.

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Conflict of interest statement

No competing interests were disclosed.

Figures

Figure 1.
Figure 1.. A timeline of SEDRIC Working Groups 2018–2023.
Six working groups have been convened and delivered analysis, advice and projects over the first five years of SEDRIC. Periods of research and publication activity, and funding are noted.
Figure 2.
Figure 2.. An overview of SEDRI-LIMS.
Figure 3.
Figure 3.. Evidence base review process and recommendations from Genomics Surveillance for AMR Working Group.
See this image and copyright information in PMC

References

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