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. 2025 Mar 3;8(3):e2461729.
doi: 10.1001/jamanetworkopen.2024.61729.

Time From Onset to Diagnosis of Alpha-Gal Syndrome

Caroline K Maki  1   2   3 , Eleanor F Saunders  1   2   4 , Marissa L Taylor  1 , Scott P Commins  5   4 , Lance A Waller  6 , Johanna S Salzer  1
Affiliations

Time From Onset to Diagnosis of Alpha-Gal Syndrome

Caroline K Maki et al. JAMA Netw Open. .
No abstract available

Plain language summary

This case series investigates trends in time from onset of alpha-gal syndrome to diagnosis among patients with disease onset from 1977 to 2019.

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Conflict of interest statement

Conflict of Interest Disclosures: Dr Saunders reported non-financial support from AAAAI Fellow travel support to attend annual conference related to separate work on alpha-gal syndrome outside the submitted work. Dr Commins reported grants from NIH - NIAID R01 AI135049 during the conduct of the study; personal fees from Genentech advisory board, personal fees from Regeneron advisory board, and personal fees from Up to Date author royalties outside the submitted work. No other disclosures were reported.

Figures

Figure.
Figure.. Diagnosis Time of Patients With AGS by First Symptom Onset and Education Level
Pin plot of the time to diagnosis of patients in the case cohort. First year of symptom onset groups based on equal quartiles of 18 and labeled based on self-reported first year of onset (P < .001). Education groups were self-reported highest level of completed education (P = .50). Time in years does not include prior to 2009. Due to the division of data in 4 equal quartiles in panel A, the years 2011, 2016, and 2019 span multiple quartiles, though each observation is distinct.
See this image and copyright information in PMC

References

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