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. 2025 May 6;333(17):1540-1543.
doi: 10.1001/jama.2025.1225.

Genomic Characterization of RSV in the US by Vaccination Status

Adam S Lauring  1 , Connor Edson  2 , Diya Surie  3 , Fatimah S Dawood  3 , Wesley H Self  4 , Cynthia Lucero-Obusan  5   6 , Mark Holodniy  2 ; IVY Network
Collaborators, Affiliations

Genomic Characterization of RSV in the US by Vaccination Status

Adam S Lauring et al. JAMA. .
No abstract available

Plain language summary

This study examines respiratory syncytial virus (RSV) genomic surveillance results from 2 large US networks after the introduction of RSV vaccines.

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Figures

Figure 1.
Figure 1.
Time resolved phylogenetic tree of RSV-B F. Time resolved maximum likelihood phylogenetic tree of 270 RSV-B sequences from US adults September 2023 – April 2024 and 70 contextual RSV-B sequences from 2022–2023 in the IVY network, available on GISAID. Tips are colored by vaccination status (purple = vaccinated, n=19; green = partial vaccinated, n=2). The heatmap shows amino acid substitutions (top) in antigenic sites identified across the cohort (yellow = present) relative to the reference sequence hRSV/B/Australia/VIC-RCH056/2019 (EPI_ISL_1653999).
See this image and copyright information in PMC

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