Coronary Arteries Involvement in Giant Cell Arteritis Diagnosis Using 2-[ 18 F]FDG-PET/CT
- PMID: 40065448
- DOI: 10.1097/RLU.0000000000005807
Coronary Arteries Involvement in Giant Cell Arteritis Diagnosis Using 2-[ 18 F]FDG-PET/CT
Abstract
Coronary artery involvement in giant cell arteritis (GCA) is rare but can lead to severe complications, including myocardial infarction and death. We present unique 2-[ 18 F]fluorodeoxyglucose positron emission tomography/computed tomography (2-[ 18 F]FDG-PET/CT) findings in a 91-year-old woman with GCA. In addition to typical aortic and supra-aortic involvement, this scan revealed intense FDG uptake in the coronary arteries, including the left main trunk, left anterior descending, circumflex, and right coronary arteries. This inflammatory pattern was consistent with GCA, with no signs of atherosclerosis on coronary CT angiography. Early identification of coronary inflammation enabled timely immunosuppressive therapy, potentially preventing fatal outcomes.
Keywords: coronary arteritis; giant cell arteritis; horton disease.
Copyright © 2025 Wolters Kluwer Health, Inc. All rights reserved.
Conflict of interest statement
Conflicts of interest and sources of funding: none declared.
References
-
- Gonzalez-Gay MA, Vazquez-Rodriguez TR, Lopez-Diaz MJ, et al. Epidemiology of giant cell arteritis and polymyalgia rheumatica. Arthristis Rheum. 2009;61:1464–1461.
-
- de Boysson H, Aouba A. An updated review of cardiovascular events in giant cell arteritis. J Clin Med. 2022;11:1005.
-
- Ray JG, Mamdani MM, Geerts WH. Giant cell arteritis and cardiovascular disease in older adults. Heart. 2005;91:324–328.
-
- Tomasson G, Peloquin C, Mohammad A, et al. Risk for cardiovascular disease early and late after a diagnosis of giant-cell arteritis. Ann Intern Med. 2014;160:73–80.
-
- Greigert H, Zeller M, Putot A, et al. Myocardial infarction during giant cell arteritis: a cohort study. Eur J Intern Med. 2021;89:30–38.
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