Wanted, but Elusive: Clear Solutions for Addressing Potential Group Harm in Data-Centric Research

Carolyn Riley Chapman^{1

2

3}, Patrick Dwyer⁴, Kellie Owens⁵, Courtney Berrios^{6

7}, Heini M Natri⁸, Arthur L Caplan⁵, Gwendolyn P Quinn⁵

Affiliations

¹ The Multi-Regional Clinical Trials Center of Brigham and Women's Hospital and Harvard.
² Brigham and Women's Hospital.
³ Harvard Medical School.
⁴ La Trobe University.
⁵ NYU Grossman School of Medicine.
⁶ Children's Mercy Kansas City.
⁷ University of Missouri-Kansas City School of Medicine.
⁸ The Translational Genomics Research Institute.

PMID: 40067136
DOI: 10.1080/15265161.2025.2470696

Free article

Comment

Wanted, but Elusive: Clear Solutions for Addressing Potential Group Harm in Data-Centric Research

Carolyn Riley Chapman et al. Am J Bioeth. 2025 Apr.

Free article

. 2025 Apr;25(4):W13-W16.

doi: 10.1080/15265161.2025.2470696. Epub 2025 Mar 11.

Authors

Carolyn Riley Chapman^{1

2

3}, Patrick Dwyer⁴, Kellie Owens⁵, Courtney Berrios^{6

7}, Heini M Natri⁸, Arthur L Caplan⁵, Gwendolyn P Quinn⁵

Affiliations

¹ The Multi-Regional Clinical Trials Center of Brigham and Women's Hospital and Harvard.
² Brigham and Women's Hospital.
³ Harvard Medical School.
⁴ La Trobe University.
⁵ NYU Grossman School of Medicine.
⁶ Children's Mercy Kansas City.
⁷ University of Missouri-Kansas City School of Medicine.
⁸ The Translational Genomics Research Institute.

PMID: 40067136
DOI: 10.1080/15265161.2025.2470696

No abstract available

PubMed Disclaimer

Comment on

Consideration and Disclosure of Group Risks in Genomics and Other Data-Centric Research: Does the Common Rule Need Revision?
Chapman CR, Quinn GP, Natri HM, Berrios C, Dwyer P, Owens K, Heraty S, Caplan AL. Chapman CR, et al. Am J Bioeth. 2025 Feb;25(2):47-60. doi: 10.1080/15265161.2023.2276161. Epub 2023 Nov 27. Am J Bioeth. 2025. PMID: 38010648 Free PMC article.
Just Tradeoffs in Health Research Decision-Making: A Gap in the Common Rule.
Callier S. Callier S. Am J Bioeth. 2025 Feb;25(2):80-82. doi: 10.1080/15265161.2024.2441731. Epub 2025 Jan 29. Am J Bioeth. 2025. PMID: 39878716 No abstract available.
Addressing Risk in Data Centric Research via Community Engagement.
Spellecy R, Nencka A. Spellecy R, et al. Am J Bioeth. 2025 Feb;25(2):85-87. doi: 10.1080/15265161.2024.2441698. Epub 2025 Jan 29. Am J Bioeth. 2025. PMID: 39878717 No abstract available.
Consensus and Solidarity: Protecting All People from Group Harms.
Yu JH. Yu JH. Am J Bioeth. 2025 Feb;25(2):71-73. doi: 10.1080/15265161.2024.2441754. Epub 2025 Jan 29. Am J Bioeth. 2025. PMID: 39878718 No abstract available.
Beyond Individual Responsibility: Group Harms in Genomic (Data-Centric) Research Ethics Require Structural, Justice-Oriented Solutions.
Eitenberger M, Baugh M, McDonald KE, Sabatello M. Eitenberger M, et al. Am J Bioeth. 2025 Feb;25(2):77-79. doi: 10.1080/15265161.2024.2441719. Epub 2025 Jan 29. Am J Bioeth. 2025. PMID: 39878720 Free PMC article. No abstract available.
Looking Beyond the IRB.
Waeiss Q, Levi M, Wenar L, Magnus D. Waeiss Q, et al. Am J Bioeth. 2025 Feb;25(2):3-5. doi: 10.1080/15265161.2025.2450982. Epub 2025 Jan 29. Am J Bioeth. 2025. PMID: 39878721 Free PMC article. No abstract available.
Why Revise When We Should Reconcile?
Peugh EE (Karuk), Brown A (Yuin Nation), Tsosie KS (Diné), Hull SC. Peugh EE (Karuk), et al. Am J Bioeth. 2025 Feb;25(2):64-67. doi: 10.1080/15265161.2024.2441757. Epub 2025 Jan 29. Am J Bioeth. 2025. PMID: 39878725 Free PMC article. No abstract available.
Common Rule Revisions to Govern Machine Learning on Indigenous Data: Implementing the Expectations.
Halmai NB, Carroll SR, Garba I, Yracheta JM, Garrison NA. Halmai NB, et al. Am J Bioeth. 2025 Feb;25(2):73-76. doi: 10.1080/15265161.2024.2441737. Epub 2025 Jan 29. Am J Bioeth. 2025. PMID: 39878726 Free PMC article. No abstract available.
From Data to Harm: Exploring Ethical and Social Implications of Polygenic Scores for Social Traits.
Cadigan RJ, Watson S, Prince AER. Cadigan RJ, et al. Am J Bioeth. 2025 Feb;25(2):82-84. doi: 10.1080/15265161.2024.2441743. Epub 2025 Jan 29. Am J Bioeth. 2025. PMID: 39878736 Free PMC article. No abstract available.
Research and Reasons: In Defense of the Common Rule's Preclusionary Statement.
Rhodes R, Blanchard O. Rhodes R, et al. Am J Bioeth. 2025 Feb;25(2):67-70. doi: 10.1080/15265161.2024.2441723. Epub 2025 Jan 29. Am J Bioeth. 2025. PMID: 39878741 No abstract available.
Beyond Individual Consent: The Hidden Crisis of Group Harm in the AI and Genomics Era.
Yang YT. Yang YT. Am J Bioeth. 2025 Feb;25(2):93-94. doi: 10.1080/15265161.2024.2441746. Epub 2025 Jan 29. Am J Bioeth. 2025. PMID: 39878742 No abstract available.
Collective Risks and the Social Disvalue of Research.
Różyńska JK. Różyńska JK. Am J Bioeth. 2025 Feb;25(2):90-93. doi: 10.1080/15265161.2024.2441724. Epub 2025 Jan 29. Am J Bioeth. 2025. PMID: 39878743 No abstract available.
Integrating Community Voices in Data-Centric Research: Overcoming Barriers to Meaningful Engagement.
Watson S, Agam P, Stroud AM, McGowan ML. Watson S, et al. Am J Bioeth. 2025 Feb;25(2):87-90. doi: 10.1080/15265161.2024.2441748. Epub 2025 Jan 29. Am J Bioeth. 2025. PMID: 39878745 No abstract available.
Group Risks: Thinking Outside the Box.
Doerr M, Meeder S. Doerr M, et al. Am J Bioeth. 2025 Feb;25(2):61-64. doi: 10.1080/15265161.2024.2441729. Epub 2025 Jan 29. Am J Bioeth. 2025. PMID: 39878747 No abstract available.

Publication types

Actions

LinkOut - more resources

Full Text Sources
- Atypon

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Wanted, but Elusive: Clear Solutions for Addressing Potential Group Harm in Data-Centric Research

Affiliations

Wanted, but Elusive: Clear Solutions for Addressing Potential Group Harm in Data-Centric Research

Authors

Affiliations

Comment on

Publication types

LinkOut - more resources

Full Text Sources