Fueling defense: PPARα enhances macrophage inflammatory responses

Affiliations

¹ Department of Medical Biochemistry, Amsterdam institute for Immunology and Infectious Diseases, Immunology, Amsterdam Cardiovascular Sciences, Atherosclerosis, Amsterdam UMC, location University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands. m.a.hoeksema@amsterdamumc.nl.

Comment

Marten A Hoeksema. Cell Mol Immunol. 2025 Apr.

. 2025 Apr;22(4):461-462.

doi: 10.1038/s41423-025-01265-y. Epub 2025 Mar 11.

¹ Department of Medical Biochemistry, Amsterdam institute for Immunology and Infectious Diseases, Immunology, Amsterdam Cardiovascular Sciences, Atherosclerosis, Amsterdam UMC, location University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands. m.a.hoeksema@amsterdamumc.nl.

No abstract available

Conflict of interest statement

Competing interests: The author declares no competing interests.

Peroxisome proliferator-activated receptor alpha is an essential factor in enhanced macrophage immune function induced by angiotensin-converting enzyme.
Saito S, Cao DY, Bernstein EA, Shibata T, Jones AE, Rios A, Hoshi AO, Stotland AB, Nishi EE, Van Eyk JE, Divakaruni A, Khan Z, Bernstein KE. Saito S, et al. Cell Mol Immunol. 2025 Mar;22(3):243-259. doi: 10.1038/s41423-025-01257-y. Epub 2025 Feb 5. Cell Mol Immunol. 2025. PMID: 39910334 Free PMC article.

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