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Review
. 2025 Feb 25:16:1536581.
doi: 10.3389/fneur.2025.1536581. eCollection 2025.

High-resolution magnetic resonance vessel wall imaging in extracranial cervical artery dissection

Affiliations
Review

High-resolution magnetic resonance vessel wall imaging in extracranial cervical artery dissection

Sai Shao et al. Front Neurol. .

Abstract

Extracranial cervical artery dissection (eCAD) is the second leading cause of stroke in young and middle-aged adults. Clinical management strategies for eCAD are continuously being explored and optimized, as revealed by the recently published CADISS and TREAT-CAD studies. The type of drug, dosage, and timing of administration can affect the regression of carotid artery dissection and the risk of recurrence of stroke. Based on imaging evidence, it is important to develop individualized treatment strategies for different risk groups. Currently, High-resolution magnetic resonance vessel wall imaging (MR-VWI) technology has made significant progress in the qualitative diagnosis of eCAD, vascular lesion progression, and the assessment of recurring ischemic stroke risk. To better understand the pathogenesis and progression of eCAD using MR-VWI, a comprehensive review is presented here.

Keywords: black blood; cervical artery dissection; intramural hematoma; ischemic stroke; vessel wall imaging.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

References

    1. Debette S, Leys D. Cervical-artery dissections: predisposing factors, diagnosis, and outcome. Lancet Neurol. (2009) 8:668–78. doi: 10.1016/S1474-4422(09)70084-5, PMID: - DOI - PubMed
    1. Markus HS, Levi C, King A, Madigan J, Norris J. For the cervical artery dissection in stroke study (CADISS) investigators. Antiplatelet therapy vs anticoagulation therapy in cervical artery dissection: the cervical artery dissection in stroke study (CADISS) randomized clinical trial final results. JAMA Neurol. (2019) 76:657–64. doi: 10.1001/jamaneurol.2019.0072, PMID: - DOI - PMC - PubMed
    1. Engelter ST, Traenka C, Gensicke H, Schaedelin SA, Luft AR, Simonetti BG, et al. Aspirin versus anticoagulation in cervical artery dissection (TREAT-CAD): an open-label, randomised, non-inferiority trial. Lancet Neurol. (2021) 20:341–50. doi: 10.1016/S1474-4422(21)00044-2, PMID: - DOI - PubMed
    1. Schievink WI. Spontaneous dissection of the carotid and vertebral arteries. N Engl J Med. (2001) 344:898–906. doi: 10.1056/NEJM200103223441206, PMID: - DOI - PubMed
    1. Schwartz NE, Vertinsky AT, Hirsch KG, Albers GW. Clinical and radiographic natural history of cervical artery dissections. J Stroke Cerebrovasc Dis. (2009) 18:416–23. doi: 10.1016/j.jstrokecerebrovasdis.2008.11.016, PMID: - DOI - PubMed

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