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Review
. 2025 Mar;43(3):397-406.
doi: 10.55563/clinexprheumatol/m0pi1k. Epub 2025 Mar 12.

Systemic lupus erythematosus: one year in review 2025

Angela Elia  1 , Dina Zucchi  1 , Ettore Silvagni  2 , Marco Oliva  1 , Giancarlo Cascarano  1 , Chiara Cardelli  1 , Benedetta Ciribè  1 , Alessandra Bortoluzzi  2 , Chiara Tani  3
Affiliations
Free article
Review

Systemic lupus erythematosus: one year in review 2025

Angela Elia et al. Clin Exp Rheumatol. 2025 Mar.
Free article

Abstract

This review highlights key advancements in systemic lupus erythematosus (SLE) research during 2024, covering pathogenesis, novel therapies, biomarkers, and clinical outcomes. Notable findings include new insights into immune dysregulation, promising therapeutic targets, and real-world data confirming the efficacy of anifrolumab and belimumab. Advances in biomarkers enhance disease monitoring, while multidisciplinary approaches improve reproductive outcomes and quality of life. These developments contribute to refining SLE treatment strategies and patient management.

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