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Practice Guideline
. 2025 Mar;23(3):113-130.
doi: 10.6004/jnccn.2025.0012.

Pediatric Central Nervous System Cancers, Version 2.2025, NCCN Clinical Practice Guidelines In Oncology

Amar Gajjar  1 , Anita Mahajan  2 , Tejus Bale  3 , Daniel C Bowers  4 , Liz Canan  2 , Susan Chi  5 , Andrew Cluster  6 , Kenneth Cohen  7 , Bonnie Cole  8 , Scott Coven  9 , Wendy Darlington  10 , Kathleen Dorris  11 , Jennifer Elster  12 , Ralph Ermoian  8 , Andrea Franson  13 , Elizabeth George  14 , Jeffrey Helgager  15 , Daniel Landi  16 , Chi Lin  17 , Laura Metrock  18 , Ronica Nanda  19 , Joshua Palmer  20 , Sonia Partap  21 , Ashley Plant  22 , Sumit Pruthi  23 , Renee Reynolds  24 , Duncan Stearns  25 , Phillip Storm  26 , Anthony Wang  27 , Leo D Wang  28 , Nicholas Whipple  29 , Wafik Zaky  30 , Nicole McMillian  31 , Swathi Ramakrishnan  31
Affiliations
Practice Guideline

Pediatric Central Nervous System Cancers, Version 2.2025, NCCN Clinical Practice Guidelines In Oncology

Amar Gajjar et al. J Natl Compr Canc Netw. 2025 Mar.

Abstract

The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Pediatric Central Nervous System Cancers provide multidisciplinary diagnostic workup, staging, and treatment recommendations for diffuse high-grade gliomas and medulloblastomas in children and adolescents. This article summarizes the studies and panel discussion that serve as the rationale for comprehensive care recommendations included in the NCCN Guidelines for Pediatric Central Nervous System Cancers.

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