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. 2025 Jun 1;21(6):1103-1107.
doi: 10.5664/jcsm.11658.

Clinical significance of sleepiness: an American Academy of Sleep Medicine position statement

Affiliations

Clinical significance of sleepiness: an American Academy of Sleep Medicine position statement

Thomas M Heffron et al. J Clin Sleep Med. .

Abstract

Alertness is a necessity for well-being and performance, and sleepiness is associated with cognitive and functional impairments that can have a negative impact on performance, health, mood, safety, and quality of life. In severe cases, sleepiness can lead to debilitation, injury, or death. Sleepiness is a marker of insufficient sleep and is the major patient-reported symptom associated with disorders of sleep and wakefulness such as narcolepsy and obstructive sleep apnea. Excessive sleepiness-the inability to stay awake and alert during the major waking episodes of the day-is reported by one third of US adults. It is the position of the American Academy of Sleep Medicine that sleepiness is a critical patient-reported outcome that is associated with increased risk for adverse health effects and diminished quality of life. The evaluation and management of sleepiness is essential for patient safety and patient-centered care. The health care system must support the evaluation and management of sleepiness so that patients can experience restorative sleep and daytime alertness. More research and innovation are needed to improve the treatment of sleep-wake disorders, including studies in diverse populations that support the development of tailored therapies for daytime sleepiness.

Citation: Heffron TM, Gurubhagavatula I, Trotti LM, et al. Clinical significance of sleepiness: an American Academy of Sleep Medicine position statement. J Clin Sleep Med. 2025;21(6):1103-1107.

Keywords: patient-reported outcomes; position statement; sleepiness.

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Conflict of interest statement

Mr. Heffron is employed by the American Academy of Sleep Medicine, and the other authors are the 2023–2024 and 2024–2025 members of the American Academy of Sleep Medicine board of directors. Dr. Martin has received consulting compensation from ResMed. Dr. Patil has received consulting compensation from Kramer Levin Naftalis & Frankel LLP for a sleep-related legal case and is key personnel on a sleep-related research or education grant from Apnimed. Dr. Wickwire has received compensation as a scientific consultant or advisor for Axsome Therapeutics, Eisai, EnsoData, Idorsia, Merck, Nox Health, Primasun, and ResMed, and he is key personnel on sleep-related research or education grants from Merck and ResMed Foundation. This statement is published by the American Academy of Sleep Medicine as an advisory that is to be used for educational and informational purposes only.

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