Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2025 Jul;59(5):495-504.
doi: 10.1177/15385744251327014. Epub 2025 Mar 13.

Endovenous Treatment for Great Saphenous Vein Insufficiency: A Comparative Study of Segmental Radiofrequency and 1470-nm Endovenous Laser

Affiliations
Randomized Controlled Trial

Endovenous Treatment for Great Saphenous Vein Insufficiency: A Comparative Study of Segmental Radiofrequency and 1470-nm Endovenous Laser

Márcio Gomes Filippo et al. Vasc Endovascular Surg. 2025 Jul.

Abstract

PurposeThis study aims to evaluate recovery time, patient-centric postoperative outcomes, and the efficacy of endovenous laser ablation (LA) and radiofrequency ablation (RFA) in treating venous insufficiency associated with great saphenous vein (GSV) reflux.MethodsIn this single-center, self-paired, randomized trial, 16 limbs from 8 patients with symptomatic bilateral GSV insufficiency were treated. LA was performed on one lower limb, and after 40 days, the contralateral limb was treated with RFA. For LA, we used a 1470-nm endolaser with radial fiber, and for RFA, the VNUS ClosureFast™ system. All patients were followed with clinical, radiological, and laboratory evaluations for 6 months postoperatively.ResultsBoth techniques showed similar postoperative pain scores, number of complications, time to return to work, and patient satisfaction scores. LA and RFA decreased the mean Venous Clinical Severity Score by the end of the study and achieved a 100% vein occlusion rate, along with a reduction in GSV size. Procedure time was significantly shorter with LA.ConclusionLA and RFA demonstrated similar recovery profiles, pain levels, and patient satisfaction outcomes, maintaining high efficacy in resolving venous insufficiency associated with GSV reflux.

Keywords: endovenous laser ablation; endovenous thermal ablation; great saphenous vein; laser 1470 nm; radial fiber; radiofrequency ablation; venous insufficiency.

PubMed Disclaimer

Conflict of interest statement

Declaration of Conflicting InterestsThe author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: T.A.B., M.G.F., and L.C.A. report receiving research grants from Merit Medical Systems, Scitech Medical©, and Bard BD, as well as consulting and lecture fees from Medtronic, Bard BD, Merit Medical Systems, Scitech Medical©, and Gore. L.O.H. reports receiving research grants from Merit Medical Systems and Bard BD and consulting or lecture fees from Medtronic, Bard BD, Merit Medical Systems, Scitech Medical©, and Gore.

Publication types

MeSH terms

LinkOut - more resources